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Toxicology and Pharmacology

RANDALL_WILLIAM

Track Leader

William Randall, Ph.D.
Bressler Research Building, Room 4-037
655 West Baltimore Street
410-706-7530
wrandall@som.umaryland.edu

Our Mission: To advance health protection through environmental health programs.

The Toxicology and Pharmacology Track offers a unique interdisciplinary graduate program, which provides training in molecular and mechanistic toxicology and the translation of basic research findings to health protection through the advancement of environmental health programs. Program faculty at multiple University of Maryland  campuses bring diverse areas of expertise to research questions that address the human and ecological impacts of natural toxins, industrial chemicals, pesticides, poisons and pharmaceuticals used in society.

Faculty Research Interests Include:

Molecular and Mechanistic Toxicology

Research opportunities in Molecular and Mechanistic Toxicology focus on mechanisms of cellular responses to drugs, environmental chemicals, and radiation in mammalian systems. Students employ state-of-the-art techniques in modern molecular biology, biochemistry, genomic sciences and pharmacology.  Transgenic and knockout animal models are used to investigate complex biological processes, including oxidative and free radical stress, cell signaling in cell survival and death, cell cycle control, and cell proliferation and differentiation. Faculty research areas include: carcinogenesis, chemoprotection, developmental abnormalities, neurologic-, cardiovascular- & renal-system toxicity, mechanisms of drug  action and drug development.

Environmental Toxicology

Research areas in Toxicology and Environmental Health include environmental epidemiology, aquatic toxicology and the effects of endocrine disruption. Research opportunities focus on health effects of ambient air particulate matter in urban and rural areas, toxicology of marine and estuary waters, and the role of genetic polymorphisms in individual susceptibility to adverse health effects of environmental and occupational chemicals.

Areas of Concentration:

  • Neurotoxicology
  • Cancer Toxicology
  • Developmental Toxicology
  • Molecular Mechanisms of Cell Injury
  • Environmental Toxicology
  • Oxidative Stress and Signaling
  • Aquatic Toxicology