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Neurodegeneration

neurodegforweb

‌Some of the cruelest and most devastating disorders known to humans are those linked to neurodegeneration, which result in the loss of neurons that are critical for body and brain function. Examples of these include Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, Prion disease, amyotrophic lateral sclerosis and other neurological and psychiatric disorders. Recent estimates suggest that one in four Americans will suffer from a neurodegenerative disorder, and this number is likely to rise because of an increase in life expectancy. Although once thought to be intractable, research into neurodegenerative diseases is yielding new clues, not only in terms of the genes and pathways that are linked to neurodegeneration, but also in ways to prevent and treat these disorders. Our current understanding of neurodegeneration indicates it is brought about by three main influences, genetic (genes), environmental, and aging itself. Modern advances in molecular, structural, computational, biochemical, electrophysiological, systems biology and stem cell techniques are providing new insight and avenues to model and treat neurodegeneration. There is great hope and excitement that the next few years will witness the development of rational therapies to treat and/or prevent neurodegenerative diseases.

Faculty

Laure Aurelian 

 

Ilia V Baskakov  

 

Alan Faden 

 

Paul Fishman 

 

Gary Fiskum 

 

L. Elliot Hong  

 

Xiaofeng Jia

 

Tibor Kristian 

 

Bruce Krueger 

 

 

Iris Lindberg 

lab website

 

Marta Lipinski

 

Mervyn Monteiro 

 

Brian Polster 

 

James Russell 

 

Robert Schwarcz

 

Bogdan Stoica