Skip to main content

2022 Publications

Publications are listed by program. Select a program or simply scroll down the page.

Biochemistry & Molecular Biology

Epidemiology & Human Genetics

Gerontology

Molecular Medicine

Molecular Microbiology & Immunology

Neuroscience

Physical Rehabilitation Science

Biochemistry & Molecular Biology

Hugo Bibollet

Morgenstern TJ, Nirwan N, Hernández-Ochoa EO, Bibollet H, Choudhury P, Laloudakis YD, Ben Johny M, Bannister RA, Schneider MF, Minor DL Jr, Colecraft HM. Selective posttranslational inhibition of CaVβ1-associated voltage-dependent calcium channels with a functionalized nanobody. Nat Commun. 2022 Dec 9;13(1):7556. doi: 10.1038/s41467-022-35025-7.

Xi Chen

Naselsky W, Adhikary G, Shrestha S, Chen X, Ezeka G, Xu W, Friedberg JS, Eckert RL. Transglutaminase 2 enhances hepatocyte growth factor signaling to drive the mesothelioma cancer cell phenotype. Mol Carcinog. 2022 Jun;61(6):537-548. doi: 10.1002/mc.23399.

Chen X, Adhikary G, Ma E, Newland JJ, Naselsky W, Xu W, Eckert RL. Sulforaphane inhibits CD44v6/YAP1/TEAD signaling to suppress the cancer phenotype. Mol Carcinog. 2022 Oct 26. doi: 10.1002/mc.23479.

Adhikary G, Shrestha S, Naselsky W, Newland JJ, Chen X, Xu W, Emadi A, Friedberg JS, Eckert RL. Mesothelioma cancer cells are glutamine addicted and glutamine restriction reduces YAP1 signaling to attenuate tumor formation. Mol Carcinog. 2022 Dec 23. doi: 10.1002/mc.23497.

Eric Choi

Fox ME, Wulff AB, Franco D, Choi EY, Calarco CA, Engeln M, Turner MD, Chandra R, Rhodes VM, Thompson SM, Ament SA, Lobo MK. Adaptations in Nucleus Accumbens Neuron Subtypes Mediate Negative Affective Behaviors in Fentanyl Abstinence. Biol Psychiatry. 2022 Aug 30:S0006-3223(22)01551-7. doi: 10.1016/j.biopsych.2022.08.023.

Engeln M, Fox ME, Chandra R, Choi EY, Nam H, Qadir H, Thomas SS, Rhodes VM, Turner MD, Herman RJ, Calarco CA, Lobo MK. Transcriptome profiling of the ventral pallidum reveals a role for pallido-thalamic neurons in cocaine reward. Mol Psychiatry. 2022 Oct;27(10):3980-3991. doi: 10.1038/s41380-022-01668-7.

Daniel Garman

Muriel J, Lukyanenko V, Kwiatkowski T, Bhattacharya S, Garman D, Weisleder N, Bloch RJ. The C2 domains of dysferlin: roles in membrane localization, Ca2+ signalling and sarcolemmal repair. J Physiol. 2022 Apr;600(8):1953-1968. doi: 10.1113/JP282648.

Lukyanenko V, Muriel J, Garman D, Breydo L, Bloch RJ. Elevated Ca2+ at the triad junction underlies dysregulation of Ca2+ signaling in dysferlin-null skeletal muscle. Front Physiol. 2022 Nov 3;13:1032447. doi: 10.3389/fphys.2022.1032447.

Rex Gonzales

Gupta A, Hwang BJ, Benyamien-Roufaeil D, Jain S, Liu S, Gonzales R, Brown RA, Zalzman M, Lu AL. Mammalian MutY Homolog (MYH or MUTYH) is Critical for Telomere Integrity under Oxidative Stress. OBM Geriat. 2022;6(2):196. doi: 10.21926/obm.geriatr.2202196.

Hwang BJ, Gonzales R, Corzine S, Stenson E, Pidugu L, Lu AL. DNA binding by the Rad9A subunit of the Rad9-Rad1-Hus1 complex. PLoS One. 2022 Aug 8;17(8):e0272645. doi: 10.1371/journal.pone.0272645.

Mitasha Palha

Palha MS, Legenzov EA, Lamb DR, Zimring JC, Buehler PW, Kao JPY. Superoxide measurement as a novel probe of red blood cell storage quality. Blood Transfus. 2022 Dec 15. doi: 10.2450/2022.0246-22.

Matthew Sherman

Servius HW, Pidugu LS, Sherman ME, Drohat AC. Rapid excision of oxidized adenine by human thymine DNA glycosylase. J Biol Chem. 2022 Nov 30;299(1):102756. doi: 10.1016/j.jbc.2022.102756.

Sherman ME, Smith RD, Gardner FM, Goodlett DR, Ernst RK. A Sensitive GC-MS Method for Quantitation of Lipid A Backbone Components and Terminal Phosphate Modifications. J Am Soc Mass Spectrom. 2022 Dec 7;33(12):2301-2309. doi: 10.1021/jasms.2c00266.

Megan Stemberger

Mathias TJ, Ju JA, Lee RM, Thompson KN, Mull ML, Annis DA, Chang KT, Ory EC, Stemberger MB, Hotta T, Ohi R, Vitolo MI, Moutin MJ, Martin SS. Tubulin Carboxypeptidase Activity Promotes Focal Gelatin Degradation in Breast Tumor Cells and Induces Apoptosis in Breast Epithelial Cells That Is Overcome by Oncogenic Signaling. Cancers (Basel). 2022 Mar 28;14(7):1707. doi: 10.3390/cancers14071707.

Maria Traficante

Bamgboye MA, Herold KG, Vieira DCO, Traficante MK, Rogers PJ, Ben-Johny M, Dick IE. CaV1.2 channelopathic mutations evoke diverse pathophysiological mechanisms. J Gen Physiol. 2022 Nov 7;154(11):e202213209. doi: 10.1085/jgp.202213209.

Bamgboye MA, Traficante MK, Owoyemi J, DiSilvestre D, Vieira DCO, Dick IE. Impaired CaV1.2 inactivation reduces the efficacy of calcium channel blockers in the treatment of LQT8. J Mol Cell Cardiol. 2022 Dec;173:92-100. doi: 10.1016/j.yjmcc.2022.10.003.

Brianna Young

Young BD, Cook ME, Costabile BK, Samanta R, Zhuang X, Sevdalis SE, Varney KM, Mancia F, Matysiak S, Lattman E, Weber DJ. Binding and Functional Folding (BFF): A Physiological Framework for Studying Biomolecular Interactions and Allostery. J Mol Biol. 2022 Dec 15;434(23):167872. doi: 10.1016/j.jmb.2022.167872.

Back to top

Epidemiology & Human Genetics

Matthew Adams

Sobota RS, Goron AR, Berry AA, Bailey JA, Coulibaly D, Adams M, Kone AK, Kouriba B, Doumbo OK, Sztein MB, Felgner PL, Plowe CV, Lyke KE, Thera MA, Travassos MA. Serologic and Cytokine Profiles of Children with Concurrent Cerebral Malaria and Severe Malarial Anemia Are Distinct from Other Subtypes of Severe Malaria. Am J Trop Med Hyg. 2022 Jun 13;107(2):315–9. doi: 10.4269/ajtmh.22-0135.

Ouattara A, Dwivedi A, Adams M, Niangaly A, Laurens MB, Nyunt MM, Plowe CV, Djimde A, Takala-Harrison S, Silva JC. An In Silico Analysis of Malaria Pre-Erythrocytic-Stage Antigens Interpreting Worldwide Genetic Data to Suggest Vaccine Candidate Variants and Epitopes. Microorganisms. 2022 May 25;10(6):1090. doi: 10.3390/microorganisms10061090.

Mungwira RG, Laurens MB, Nyangulu W, Divala TH, Nampota-Nkomba N, Buchwald AG, Nyirenda OM, Mwinjiwa E, Kanjala M, Galileya LT, Earland DE, Adams M, Plowe CV, Taylor TE, Mallewa J, van Oosterhout JJ, Laufer MK; TSCQ Study Team. High burden of malaria among Malawian adults on antiretroviral therapy after discontinuing prophylaxis. AIDS. 2022 Oct 1;36(12):1675-1682. doi: 10.1097/QAD.0000000000003317.

David Annis

Mathias TJ, Ju JA, Lee RM, Thompson KN, Mull ML, Annis DA, Chang KT, Ory EC, Stemberger MB, Hotta T, Ohi R, Vitolo MI, Moutin MJ, Martin SS. Tubulin Carboxypeptidase Activity Promotes Focal Gelatin Degradation in Breast Tumor Cells and Induces Apoptosis in Breast Epithelial Cells That Is Overcome by Oncogenic Signaling. Cancers (Basel). 2022 Mar 28;14(7):1707. doi: 10.3390/cancers14071707.

Sarah Brown

France M, Alizadeh M, Brown S, Ma B, Ravel J. Towards a deeper understanding of the vaginal microbiota. Nat Microbiol. 2022 Mar;7(3):367-378. doi: 10.1038/s41564-022-01083-2.

France MT, Brown SE, Rompalo AM, Brotman RM, Ravel J. Identification of shared bacterial strains in the vaginal microbiota of related and unrelated reproductive-age mothers and daughters using genome-resolved metagenomics. PLoS One. 2022 Oct 26;17(10):e0275908. doi: 10.1371/journal.pone.0275908.

Brown SE, He X, Shardell MD, Ravel J, Ghanem KG, Zenilman JM, Brotman RM. Douching cessation and molecular bacterial vaginosis: a reanalysis of archived specimens. Sex Transm Infect. 2022 May 30:sextrans-2022-055459. doi: 10.1136/sextrans-2022-055459.

Kimberly Claeys

Mody L, Akinboyo IC, Babcock HM, Bischoff WE, Cheng VC, Chiotos K, Claeys KC, Coffey KC, Diekema DJ, Donskey CJ, Ellingson KD, Gilmartin HM, Gohil SK, Harris AD, Keller SC, Klein EY, Krein SL, Kwon JH, Lauring AS, Livorsi DJ, Lofgren ET, Merrill K, Milstone AM, Monsees EA, Morgan DJ, Perri LP, Pfeiffer CD, Rock C, Saint S, Sickbert-Bennett E, Skelton F, Suda KJ, Talbot TR, Vaughn VM, Weber DJ, Wiemken TL, Yassin MH, Ziegler MJ, Anderson DJ; SHEA Research Committee. Coronavirus disease 2019 (COVID-19) research agenda for healthcare epidemiology. Infect Control Hosp Epidemiol. 2022 Feb;43(2):156-166. doi: 10.1017/ice.2021.25.

Chang J, Patel D, Vega A, Claeys KC, Heil EL, Scheetz MH. Does calculation method matter for targeting vancomycin area under the curve? J Antimicrob Chemother. 2022 Jul 28;77(8):2245-2250. doi: 10.1093/jac/dkac151.

Sullivan KV, Gallagher JC, Leekha S, Morgan DJ, Morita K, Rock C, Claeys KC. Use of diagnostic and antimicrobial stewardship practices to improve Clostridioides difficile testing among SHEA Research Network hospitals. Infect Control Hosp Epidemiol. 2022 Jul;43(7):930-934. doi: 10.1017/ice.2021.133.

Kenaa B, O'Hara NN, O'Hara LM, Claeys KC, Leekha S. Understanding healthcare provider preferences for ordering respiratory cultures to diagnose ventilator associated pneumonia: A discrete choice experiment. Antimicrob Steward Healthc Epidemiol. 2022 Jul 15;2(1):e120. doi: 10.1017/ash.2022.267.

Rock C, Perlmutter R, Blythe D, Bork J, Claeys K, Cosgrove SE, Dzintars K, Fabre V, Harris AD, Heil E, Hsu YJ, Keller S, Maragakis LL, Milstone AM, Morgan DJ, Dullabh P, Ubri PS, Rotondo C, Brooks R, Leekha S. Impact of Statewide Prevention and Reduction of Clostridioides difficile (SPARC), a Maryland public health-academic collaborative: an evaluation of a quality improvement intervention. BMJ Qual Saf. 2022 Feb;31(2):153-162. doi: 10.1136/bmjqs-2021-014014.

Noval MM, Leekha S, Armahizer M, Celotto A, Bhatt M, Seung H, Claeys K. Evaluating the incidence of bacteriuria in female patients before and after implementation of external urinary collection devices. Antimicrob Steward Healthc Epidemiol. 2022 Mar 17;2(1):e44. doi: 10.1017/ash.2022.30

Goodman KE, Heil EL, Claeys KC, Banoub M, Bork JT. Real-world Antimicrobial Stewardship Experience in a Large Academic Medical Center: Using Statistical and Machine Learning Approaches to Identify Intervention "Hotspots" in an Antibiotic Audit and Feedback Program. Open Forum Infect Dis. 2022 Jun 10;9(7):ofac289. doi: 10.1093/ofid/ofac289.

Advani SD, Claeys K. Cefepime/Enmetazobactam for Complicated Urinary Tract Infections. JAMA. 2022 Oct 4;328(13):1299-1301. doi: 10.1001/jama.2022.15228.

Buzzalino LG, Mease J, Bernhardi CL, Bork JT, Johnson JK, Claeys KC. Follow-up Blood Culture Practices for Gram-Negative Bloodstream Infections in Immunocompromised Hosts at a Large Academic Medical Center. Open Forum Infect Dis. 2022 Apr 15;9(5):ofac173. doi: 10.1093/ofid/ofac173.

O'Hara NN, Carullo J, Joshi M, Banoub M, Claeys KC, Sprague S, Slobogean GP, O'Toole RV; PREP-IT Investigators. Does cumulative topical antibiotic powder use increase the risk of drug induced acute kidney injury in fracture patients? Bone Jt Open. 2022 Apr;3(4):284-290. doi: 10.1302/2633-1462.34.BJO-2022-0009.R1.

Zasowski EJ, Trinh TD, Claeys KC, Lagnf AM, Bhatia S, Klinker KP, Veve MP, Estrada SJ, Johns ST, Sawyer AJ, Huang V, LaFrance B, Levine DP, Kaye KS, Davis SL, Rybak MJ. Multicenter Cohort Study of Ceftaroline Versus Daptomycin for Treatment of Methicillin-Resistant Staphylococcus aureus Bloodstream Infection. Open Forum Infect Dis. 2021 Dec 23;9(3):ofab606. doi: 10.1093/ofid/ofab606.

Claeys KC, Trautner BW, Leekha S, Coffey KC, Crnich CJ, Diekema DJ, Fakih MG, Goetz MB, Gupta K, Jones MM, Leykum L, Liang SY, Pineles L, Pleiss A, Spivak ES, Suda KJ, Taylor JM, Rhee C, Morgan DJ. Optimal Urine Culture Diagnostic Stewardship Practice-Results from an Expert Modified-Delphi Procedure. Clin Infect Dis. 2022 Aug 31;75(3):382-389. doi: 10.1093/cid/ciab987.

Kathleen Gwilliam

Taiber S, Gwilliam K, Hertzano R, Avraham KB. The Genomics of Auditory Function and Disease. Annu Rev Genomics Hum Genet. 2022 Aug 31;23:275-299. doi: 10.1146/annurev-genom-121321-094136.

Shisi He

He S, Berndt SI, Kunzmann AT, Kitahara CM, Huang WY, Barry KH. Weight Change and Incident Distal Colorectal Adenoma Risk in the PLCO Cancer Screening Trial. JNCI Cancer Spectr. 2022 Feb 1;6(1):pkab098. doi: 10.1093/jncics/pkab098.

Gulam Kibria

Kibria GMA, Das Gupta R, Crispen R. Association of leisure-time physical activity with perceived general health status among hypertensive people: an analysis of NHANES 2015-18. J Hum Hypertens. 2022 Mar;36(3):280-288. doi: https://doi.org/10.1038/s41371-021-00518-3.

Jindal G, Almardawi R, Gupta R, Colby GP, Schirmer CM, Satti SR, Pukenas B, Hui FK, Caplan J, Miller T, Cherian J, Aldrich F, Kibria G, Simard JM; ULTRA Study Investigators. Target Ultra and Nano coils in the endovascular treatment of small intracranial aneurysms (ULTRA Registry). J Neurosurg. 2022 Jun 24;138(1):233-240. doi: 10.3171/2022.5.JNS2296.

Gita Nadimpalli

Pineles BL, Goodman KE, Pineles L, O'Hara LM, Nadimpalli G, Magder LS, Baghdadi JD, Parchem JG, Harris AD. Pregnancy and the Risk of In-Hospital Coronavirus Disease 2019 (COVID-19) Mortality. Obstet Gynecol. 2022 May 1;139(5):846-854. doi: 10.1097/AOG.0000000000004744.

Ma B, Sundararajan S, Nadimpalli G, France M, McComb E, Rutt L, Lemme-Dumit JM, Janofsky E, Roskes LS, Gajer P, Fu L, Yang H, Humphrys M, Tallon LJ, Sadzewicz L, Pasetti MF, Ravel J, Viscardi RM. Highly Specialized Carbohydrate Metabolism Capability in Bifidobacterium Strains Associated with Intestinal Barrier Maturation in Early Preterm Infants. mBio. 2022 Jun 28;13(3):e0129922. doi: 10.1128/mbio.01299-22.

Nadimpalli G, O'Hara LM, Magder LS, Johnson JK, Haririan A, Pineles L, Goodman KE, Baghdadi JD, Pineles BL, Harris AD. Comorbidities associated with 30-day readmission following index coronavirus disease 2019 (COVID-19) hospitalization: A retrospective cohort study of 331,136 patients in the United States. Infect Control Hosp Epidemiol. 2022 Oct 3:1-9. doi: 10.1017/ice.2022.232.

Richard Smith

Sherman ME, Smith RD, Gardner FM, Goodlett DR, Ernst RK. A Sensitive GC-MS Method for Quantitation of Lipid A Backbone Components and Terminal Phosphate Modifications. J Am Soc Mass Spectrom. 2022 Dec 7;33(12):2301-2309. doi: 10.1021/jasms.2c00266.

Yang H, Smith RD, Chandler CE, Johnson JK, Jackson SN, Woods AS, Scott AJ, Goodlett DR, Ernst RK. Lipid A Structural Determination from a Single Colony. Anal Chem. 2022 May 31;94(21):7460-7465. doi: 10.1021/acs.analchem.1c05394.

Ha M, Ngaage LM, Smith RD, Izac JR, Kim PC, Singh D, Slezak S, Ernst RK, Harro J, Rasko YM. An In Vitro Model of the Efficacy of Breast Implant Irrigant Solutions Against Gram-Negative Infections. Ann Plast Surg. 2022 Dec 1;89(6):679-683. doi: 10.1097/SAP.0000000000003302.

Smith RD, McElheny CL, Izac JR, Gardner FM, Chandler CE, Goodlett DR, Doi Y, Johnson JK, Ernst RK. A Novel Lipid-Based MALDI-TOF Assay for the Rapid Detection of Colistin-Resistant Enterobacter Species. Microbiol Spectr. 2022 Feb 23;10(1):e0144521. doi: 10.1128/spectrum.01445-21.

Bray AS, Smith RD, Hudson AW, Hernandez GE, Young TM, George HE, Ernst RK, Zafar MA. MgrB-Dependent Colistin Resistance in Klebsiella pneumoniae Is Associated with an Increase in Host-to-Host Transmission. mBio. 2022 Apr 26;13(2):e0359521. doi: 10.1128/mbio.03595-21.

Yang H, Smith RD, Sumner KP, Goodlett DR, Johnson JK, Ernst RK. A Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry Direct-from-Urine-Specimen Diagnostic for Gram-Negative Pathogens. Microbiol Spectr. 2022 Dec 21;10(6):e0373022. doi: 10.1128/spectrum.03730-22.

William Still

Samson ME, Still WL, Mark-Carew M, Jarris DK, Idris A, van Zyl A, Addo D, Ashley P, Ike OJ, Thomas ES, Mangla AT, Nesbitt LS. Utility of a Test-to-Return Strategy to Identify Individuals With Coronavirus Disease 2019 (COVID-19) in the Prekindergarten Through Grade 12 School Setting-District of Columbia, January 2022. Clin Infect Dis. 2022 Oct 3;75(Suppl 2):S231-S235. doi: 10.1093/cid/ciac440. Erratum in: Clin Infect Dis. 2022 Nov 30;75(11):2051.

Back to top

Gerontology

Rachel McPherson

Resnick B, Galik E, McPherson R, Boltz M, Van Haitsma K, Kolanowski A. Gender Differences in Disease, Function, and Behavioral Symptoms in Residents with Dementia. West J Nurs Res. 2022 Sep;44(9):812-821. doi: 10.1177/01939459211018822.

Shalini Sahoo

Mayorga-Carlin M, Shaw P, Ozsvath K, Erben Y, Wang G, Sahoo S, Macdonald S, Kashyap VS, Sorkin JD, Lal BK. Transcarotid revascularization outcomes do not differ by patient age or sex. J Vasc Surg. 2022 Jul;76(1):209-219.e2. doi: 10.1016/j.jvs.2022.01.141.

Hayssen H, Cires-Drouet R, Englum B, Nguyen P, Sahoo S, Mayorga-Carlin M, Siddiqui T, Turner D, Yesha Y, Sorkin JD, Lal BK. Systematic review of venous thromboembolism risk categories derived from Caprini score. J Vasc Surg Venous Lymphat Disord. 2022 Nov;10(6):1401-1409.e7. doi: 10.1016/j.jvsv.2022.05.003.

Lal BK, Mayorga-Carlin M, Kashyap V, Jordan W, Mukherjee D, Cambria R, Moore W, Neville RF, Eckstein HH, Sahoo S, Macdonald S, Sorkin JD. Learning curve and proficiency metrics for transcarotid artery revascularization. J Vasc Surg. 2022 Jan 19:S0741-5214(22)00042-8. doi: 10.1016/j.jvs.2021.12.073.

Prasad NK, Englum BR, Mayorga-Carlin M, Turner DJ, Sahoo S, Sorkin JD, Lal BK. Partial COVID-19 vaccination associated with reduction in postoperative mortality and SARS-CoV-2 infection. Am J Surg. 2022 Oct;224(4):1097-1102. doi: 10.1016/j.amjsurg.2022.03.038.

Back to top

Molecular Medicine

Robert Brown

Gupta A, Hwang BJ, Benyamien-Roufaeil D, Jain S, Liu S, Gonzales R, Brown RA, Zalzman M, Lu AL. Mammalian MutY Homolog (MYH or MUTYH) is Critical for Telomere Integrity under Oxidative Stress. OBM Geriat. 2022;6(2):196. doi: 10.21926/obm.geriatr.2202196.

Arad M, Brown RA, Khatri R, Taylor RJ, Zalzman M. Direct differentiation of tonsillar biopsy-derived stem cells to the neuronal lineage. Cell Mol Biol Lett. 2021 Aug 18;26(1):38. doi: 10.1186/s11658-021-00279-4.

Heather Buck

Martinez R 3rd, Huang W, Buck H, Rea S, Defnet AE, Kane MA, Shapiro P. Proteomic Changes in the Monolayer and Spheroid Melanoma Cell Models of Acquired Resistance to BRAF and MEK1/2 Inhibitors. ACS Omega. 2022 Jan 18;7(4):3293-3311. doi: 10.1021/acsomega.1c05361.

Katarina Chang

Thompson KN, Ju JA, Ory EC, Pratt SJP, Lee RM, Mathias TJ, Chang KT, Lee CJ, Goloubeva OG, Bailey PC, Chakrabarti KR, Jewell CM, Vitolo MI, Martin SS. Microtubule disruption reduces metastasis more effectively than primary tumor growth. Breast Cancer Res. 2022 Feb 14;24(1):13. doi: 10.1186/s13058-022-01506-2.

Mathias TJ, Ju JA, Lee RM, Thompson KN, Mull ML, Annis DA, Chang KT, Ory EC, Stemberger MB, Hotta T, Ohi R, Vitolo MI, Moutin MJ, Martin SS. Tubulin Carboxypeptidase Activity Promotes Focal Gelatin Degradation in Breast Tumor Cells and Induces Apoptosis in Breast Epithelial Cells That Is Overcome by Oncogenic Signaling. Cancers (Basel). 2022 Mar 28;14(7):1707. doi: 10.3390/cancers14071707.

Taylor Crawford

Johnson AA, Crawford TR, Trudeau MC. The N-linker region of hERG1a upregulates hERG1b potassium channels. J Biol Chem. 2022 Sep;298(9):102233. doi: 10.1016/j.jbc.2022.102233

Brittany Hazzard

Hazzard B, Sá JM, Ellis AC, Pascini TV, Amin S, Wellems TE, Serre D. Long read single cell RNA sequencing reveals the isoform diversity of Plasmodium vivax transcripts. PLoS Negl Trop Dis. 2022 Dec 16;16(12):e0010991. doi: 10.1371/journal.pntd.0010991.

Kevin Herold

Bamgboye MA, Herold KG, Vieira DCO, Traficante MK, Rogers PJ, Ben-Johny M, Dick IE. CaV1.2 channelopathic mutations evoke diverse pathophysiological mechanisms. J Gen Physiol. 2022 Nov 7;154(11):e202213209. doi: 10.1085/jgp.202213209.

Pranjali Kanvinde

Pandey N, Anastasiadis P, Carney CP, Kanvinde PP, Woodworth GF, Winkles JA, Kim AJ. Nanotherapeutic treatment of the invasive glioblastoma tumor microenvironment. Adv Drug Deliv Rev. 2022 Sep;188:114415. doi: 10.1016/j.addr.2022.114415.

Jeffrey Koenig

Ruff AL, Causey RD, Koenig JA, LaGrasta CV, Gomez AM, Chalmers BT, Lehman JG 3rd. siRNA high throughput screening identifies regulators of chloropicrin and hydrogen fluoride injury in human corneal epithelial cell models. Exp Eye Res. 2022 Sep;222:109169. doi: 10.1016/j.exer.2022.109169.

Robert Lease

Hasin N, Riggs LM, Shekhtman T, Ashworth J, Lease R, Oshone RT, Humphries EM, Badner JA, Thomson PA, Glahn DC, Craig DW, Edenberg HJ, Gershon ES, McMahon FJ, Nurnberger JI, Zandi PP, Kelsoe JR, Roach JC, Gould TD, Ament SA. Rare variants implicate NMDA receptor signaling and cerebellar gene networks in risk for bipolar disorder. Mol Psychiatry. 2022 Sep;27(9):3842-3856. doi: 10.1038/s41380-022-01609-4.

Kanwal Mahmood

Kapadia B, Shetty AC, Bollino D, Bhandary B, Lapidus RG, Mahmood K, Mahurkar A, Gartenhaus RB, Eckert RL, Emadi A. Translatome changes in acute myeloid leukemia cells post exposure to pegcrisantaspase and venetoclax. Exp Hematol. 2022 Jan 31:S0301-472X(22)00036-4. doi: 10.1016/j.exphem.2022.01.006.

Paige McKeon

McKeon PN, Bunce GW, Patton MH, Chen R, Mathur BN. Cortical control of striatal fast-spiking interneuron synchrony. J Physiol. 2022 May;600(9):2189-2202. doi: 10.1113/JP282850.

Makenzy Mull

Mathias TJ, Ju JA, Lee RM, Thompson KN, Mull ML, Annis DA, Chang KT, Ory EC, Stemberger MB, Hotta T, Ohi R, Vitolo MI, Moutin MJ, Martin SS. Tubulin Carboxypeptidase Activity Promotes Focal Gelatin Degradation in Breast Tumor Cells and Induces Apoptosis in Breast Epithelial Cells That Is Overcome by Oncogenic Signaling. Cancers (Basel). 2022 Mar 28;14(7):1707. doi: 10.3390/cancers14071707.

Blair Ptak

Cook AL, Wyhs N, Sur S, Ptak B, Popoli M, Dobbyn L, Papadopoulos T, Bettegowda C, Papadopoulos N, Vogelstein B, Zhou S, Kinzler KW. An isogenic cell line panel for sequence-based screening of targeted anticancer drugs. iScience. 2022 May 23;25(6):104437. doi: 10.1016/j.isci.2022.104437.

Andrea Romanowski

Altas B, Romanowski AJ, Bunce GW, Poulopoulos A. Neuronal mTOR Outposts: Implications for Translation, Signaling, and Plasticity. Front Cell Neurosci. 2022 Apr 7;16:853634. doi: 10.3389/fncel.2022.853634.

Iffland PH, Everett ME, Cobb-Pitstick KM, Bowser LE, Barnes AE, Babus JK, Romanowski AJ, Baybis M, Elziny S, Puffenberger EG, Gonzaga-Jauregui C, Poulopoulos A, Carson VJ, Crino PB. NPRL3 loss alters neuronal morphology, mTOR localization, cortical lamination and seizure threshold. Brain. 2022 Nov 21;145(11):3872-3885. doi: 10.1093/brain/awac044.

Jacob Shaw

Shaw J, Pearson RM. Nanoparticle personalized biomolecular corona: implications of pre-existing conditions for immunomodulation and cancer. Biomater Sci. 2022 May 17;10(10):2540-2549. doi: 10.1039/d2bm00315e.

Truong N, Goodis CC, Cottingham AL, Shaw JR, Fletcher S, Pearson RM. Modified Suberoylanilide Hydroxamic Acid Reduced Drug-Associated Immune Cell Death and Organ Damage under Lipopolysaccharide Inflammatory Challenge. ACS Pharmacol Transl Sci. 2022 Oct 10;5(11):1128-1141. doi: 10.1021/acsptsci.2c00119.

Nicolas Verhoeven

Karbowski M, Oshima Y, Verhoeven N. Mitochondrial proteotoxicity: implications and ubiquitin-dependent quality control mechanisms. Cell Mol Life Sci. 2022 Oct 29;79(11):574. doi: 10.1007/s00018-022-04604-8.

Mashhood Wani

Zhang JM, Au DT, Sawada H, Franklin MK, Moorleghen JJ, Howatt DA, Wang P, Aicher BO, Hampton B, Migliorini M, Ni F, Mullick AE, Wani MM, Ucuzian AA, Lu HS, Muratoglu SC, Daugherty A, Strickland DK. LRP1 protects against excessive superior mesenteric artery remodeling by modulating angiotensin II-mediated signaling. JCI Insight. 2022 Dec 6:e164751. doi: 10.1172/jci.insight.164751.

Back to top

Molecular Microbiology & Immunology

Elizabeth Hill

Abdi K, Laky K, Abshari M, Hill EM, Lantz L, Singh NJ, Long EO. Dendritic cells Trigger IFN-γ secretion by NK cells independent of IL-12 and IL-18. Eur J Immunol. 2022 Sep;52(9):1431-1440. doi: 10.1002/eji.202149733.

Casey Hofstaedter

Gerster T, Wröbel M, Hofstaedter CE, Schwudke D, Ernst RK, Ranf S, Gisch N. Remodeling of Lipid A in Pseudomonas syringae pv. phaseolicola In Vitro. Int J Mol Sci. 2022 Feb 11;23(4):1996. doi: 10.3390/ijms23041996.

Wong Fok Lung T, Charytonowicz D, Beaumont KG, Shah SS, Sridhar SH, Gorrie CL, Mu A, Hofstaedter CE, Varisco D, McConville TH, Drikic M, Fowler B, Urso A, Shi W, Fucich D, Annavajhala MK, Khan IN, Oussenko I, Francoeur N, Smith ML, Stockwell BR, Lewis IA, Hachani A, Upadhyay Baskota S, Uhlemann AC, Ahn D, Ernst RK, Howden BP, Sebra R, Prince A. Klebsiella pneumoniae induces host metabolic stress that promotes tolerance to pulmonary infection. Cell Metab. 2022 May 3;34(5):761-774.e9. doi: 10.1016/j.cmet.2022.03.009.

Gerster T, Wröbel M, Hofstaedter CE, Schwudke D, Ernst RK, Ranf S, Gisch N. Remodeling of Lipid A in Pseudomonas syringae pv. phaseolicola In Vitro. Int J Mol Sci. 2022 Feb 11;23(4):1996. doi: 10.3390/ijms23041996.

Nordstrom HR, Evans DR, Finney AG, Westbrook KJ, Zamora PF, Hofstaedter CE, Yassin MH, Pradhan A, Iovleva A, Ernst RK, Bomberger JM, Shields RK, Doi Y, Van Tyne D. Genomic characterization of lytic bacteriophages targeting genetically diverse Pseudomonas aeruginosa clinical isolates. iScience. 2022 May 10;25(6):104372. doi: 10.1016/j.isci.2022.104372.

Jessica Allen

Brammer J, Wolf G, Baliban SM, Allen JC, Choi M, Kambouris AR, Simon R, Fiskum G, Chao W, Lopez K, Miller C, Singh NJ, Cross AS. A Nonlethal Full-Thickness Flame Burn Produces a Seroma Beneath the Forming Eschar, Thereby Promoting Pseudomonas aeruginosa Sepsis in Mice. J Burn Care Res. 2022 Jul 1;43(4):792-801. doi: 10.1093/jbcr/irab195.

Corbin Goerlich

Goerlich CE, Singh A, Treffalls JA, Griffith B, Ayares D, Mohiuddin MM. An intrinsic link to an extrinsic cause of cardiac xenograft growth after xenotransplantation: Commentary (in response to): Zaman, R. et al. Selective loss of resident macrophage-derived insulin-like growth factor-1 abolishes adaptive cardiac growth to stress. Immunity 54, 2057-2071.e6 (2021).: Commentary (in response to): Zaman, R. et al. Selective loss of resident macrophage-derived insulin-like growth factor-1 abolishes adaptive cardiac growth to stress. Immunity 54, 2057-2071.e6 (2021). Xenotransplantation. 2022 Jan;29(1):e12724. doi: 10.1111/xen.12724.

Elizabeth Hill

Abdi K, Laky K, Abshari M, Hill EM, Lantz L, Singh NJ, Long EO. Dendritic cells Trigger IFN-γ secretion by NK cells independent of IL-12 and IL-18. Eur J Immunol. 2022 Sep;52(9):1431-1440. doi: 10.1002/eji.202149733.

Casey Hofstaedter

Gerster T, Wröbel M, Hofstaedter CE, Schwudke D, Ernst RK, Ranf S, Gisch N. Remodeling of Lipid A in Pseudomonas syringae pv. phaseolicola In Vitro. Int J Mol Sci. 2022 Feb 11;23(4):1996. doi: 10.3390/ijms23041996.

Adrienne Kambouris

Brammer J, Wolf G, Baliban SM, Allen JC, Choi M, Kambouris AR, Simon R, Fiskum G, Chao W, Lopez K, Miller C, Singh NJ, Cross AS. A Nonlethal Full-Thickness Flame Burn Produces a Seroma Beneath the Forming Eschar, Thereby Promoting Pseudomonas aeruginosa Sepsis in Mice. J Burn Care Res. 2022 Jul 1;43(4):792-801. doi: 10.1093/jbcr/irab195.

Verhoeve VI, Brammer JA, Driscoll TP, Kambouris AR, Rasko DA, Cross AS, Gillespie JJ. Genome Sequencing of Pseudomonas aeruginosa strain M2 illuminates traits of an opportunistic pathogen of burn wounds. G3 (Bethesda). 2022 Mar 28:jkac073. doi: 10.1093/g3journal/jkac073.

James Logue

DeGrace MM, Ghedin E, Frieman MB, Krammer F, Grifoni A, Alisoltani A, Alter G, Amara RR, Baric RS, Barouch DH, Bloom JD, Bloyet LM, Bonenfant G, Boon ACM, Boritz EA, Bratt DL, Bricker TL, Brown L, Buchser WJ, Carreño JM, Cohen-Lavi L, Darling TL, Davis-Gardner ME, Dearlove BL, Di H, Dittmann M, Doria-Rose NA, Douek DC, Drosten C, Edara VV, Ellebedy A, Fabrizio TP, Ferrari G, Fischer WM, Florence WC, Fouchier RAM, Franks J, García-Sastre A, Godzik A, Gonzalez-Reiche AS, Gordon A, Haagmans BL, Halfmann PJ, Ho DD, Holbrook MR, Huang Y, James SL, Jaroszewski L, Jeevan T, Johnson RM, Jones TC, Joshi A, Kawaoka Y, Kercher L, Koopmans MPG, Korber B, Koren E, Koup RA, LeGresley EB, Lemieux JE, Liebeskind MJ, Liu Z, Livingston B, Logue JP, Luo Y, McDermott AB, McElrath MJ, Meliopoulos VA, Menachery VD, Montefiori DC, Mühlemann B, Munster VJ, Munt JE, Nair MS, Netzl A, Niewiadomska AM, O'Dell S, Pekosz A, Perlman S, Pontelli MC, Rockx B, Rolland M, Rothlauf PW, Sacharen S, Scheuermann RH, Schmidt SD, Schotsaert M, Schultz-Cherry S, Seder RA, Sedova M, Sette A, Shabman RS, Shen X, Shi PY, Shukla M, Simon V, Stumpf S, Sullivan NJ, Thackray LB, Theiler J, Thomas PG, Trifkovic S, Türeli S, Turner SA, Vakaki MA, van Bakel H, VanBlargan LA, Vincent LR, Wallace ZS, Wang L, Wang M, Wang P, Wang W, Weaver SC, Webby RJ, Weiss CD, Wentworth DE, Weston SM, Whelan SPJ, Whitener BM, Wilks SH, Xie X, Ying B, Yoon H, Zhou B, Hertz T, Smith DJ, Diamond MS, Post DJ, Suthar MS. Defining the risk of SARS-CoV-2 variants on immune protection. Nature. 2022 May;605(7911):640-652. doi: 10.1038/s41586-022-04690-5.

Shen WB, Elahi M, Logue J, Yang P, Baracco L, Reece EA, Wang B, Li L, Blanchard TG, Han Z, Rissman RA, Frieman MB, Yang P. SARS-CoV-2 invades cognitive centers of the brain and induces Alzheimer's-like neuropathology. bioRxiv [Preprint]. 2022 Sep 6:2022.01.31.478476. doi: 10.1101/2022.01.31.478476.

Si L, Bai H, Oh CY, Jiang A, Hong F, Zhang T, Ye Y, Jordan TX, Logue J, McGrath M, Belgur C, Calderon K, Nurani A, Cao W, Carlson KE, Prantil-Baun R, Gygi SP, Yang D, Jonsson CB, tenOever BR, Frieman M, Ingber DE. Self-assembling short immunostimulatory duplex RNAs with broad-spectrum antiviral activity. Mol Ther Nucleic Acids. 2022 Sep 13;29:923-940. doi: 10.1016/j.omtn.2022.08.031.

Johnson RM, Ardanuy J, Hammond H, Logue J, Jackson L, Baracco L, McGrath M, Dillen C, Patel N, Smith G, Frieman M. Diet Induced Obesity and Diabetes Enhance Mortality and Reduces Vaccine Efficacy for SARS-CoV-2. bioRxiv [Preprint]. 2022 Oct 17:2022.10.15.512291. doi: 10.1101/2022.10.15.512291.

Logue J, Chakraborty AR, Johnson R, Goyal G, Rodas M, Taylor LJ, Baracco L, McGrath ME, Haupt R, Furlong BA, Soong M, Prabhala P, Horvath V, Carlson KE, Weston S, Ingber DE, DePamphilis ML, Frieman MB. PIKfyve-specific inhibitors restrict replication of multiple coronaviruses in vitro but not in a murine model of COVID-19. Commun Biol. 2022 Aug 12;5(1):808. doi: 10.1038/s42003-022-03766-2.

Liu DX, Cooper TK, Perry DL, Huzella LM, Hischak AMW, Hart RJ, Isic N, Byrum R, Ragland D, St Claire M, Cooper K, Reeder R, Logue J, Jahrling PB, Holbrook MR, Bennett RS, Hensley LE. Expanded Histopathology and Tropism of Ebola Virus in the Rhesus Macaque Model: Potential for Sexual Transmission, Altered Adrenomedullary Hormone Production, and Early Viral Replication in Liver. Am J Pathol. 2022 Jan;192(1):121-129. doi: 10.1016/j.ajpath.2021.09.009.

Sajadi MM, Myers A, Logue J, Saadat S, Shokatpour N, Quinn J, Newman M, Deming M, Rikhtegaran Tehrani Z, Magder LS, Karimi M, Abbasi A, Shlyak M, Baracco L, Frieman MB, Crotty S, Harris AD. Mucosal and Systemic Responses to Severe Acute Respiratory Syndrome Coronavirus 2 Vaccination Determined by Severity of Primary Infection. mSphere. 2022 Dec 21;7(6):e0027922. doi: 10.1128/msphere.00279-22.

Sperry MM, Oskotsky T, MariÄ I, Kaushal S, Takeda T, Horvath V, Powers RK, Rodas M, Furlong B, Soong M, Prabhala P, Goyal G, Carlson KE, Wong RJ, Kosti I, Le BL, Logue J, Hammond H, Frieman M, Stevenson DK, Ingber DE, Sirota M, Novak R. Target-agnostic drug prediction integrated with medical record analysis uncovers differential associations of statins with increased survival in COVID-19 patients. medRxiv [Preprint]. 2022 Jul 22:2022.04.12.22273802. doi: 10.1101/2022.04.12.22273802.

Marisa McGrath

Borriello F, Poli V, Shrock E, Spreafico R, Liu X, Pishesha N, Carpenet C, Chou J, Di Gioia M, McGrath ME, Dillen CA, Barrett NA, Lacanfora L, Franco ME, Marongiu L, Iwakura Y, Pucci F, Kruppa MD, Ma Z, Lowman DW, Ensley HE, Nanishi E, Saito Y, O'Meara TR, Seo HS, Dhe-Paganon S, Dowling DJ, Frieman M, Elledge SJ, Levy O, Irvine DJ, Ploegh HL, Williams DL, Zanoni I. An adjuvant strategy enabled by modulation of the physical properties of microbial ligands expands antigen immunogenicity. Cell. 2022 Feb 17;185(4):614-629.e21. doi: 10.1016/j.cell.2022.01.009.

Si L, Bai H, Oh CY, Jiang A, Hong F, Zhang T, Ye Y, Jordan TX, Logue J, McGrath M, Belgur C, Calderon K, Nurani A, Cao W, Carlson KE, Prantil-Baun R, Gygi SP, Yang D, Jonsson CB, tenOever BR, Frieman M, Ingber DE. Self-assembling short immunostimulatory duplex RNAs with broad-spectrum antiviral activity. Mol Ther Nucleic Acids. 2022 Sep 13;29:923-940. doi: 10.1016/j.omtn.2022.08.031.

Johnson RM, Ardanuy J, Hammond H, Logue J, Jackson L, Baracco L, McGrath M, Dillen C, Patel N, Smith G, Frieman M. Diet Induced Obesity and Diabetes Enhance Mortality and Reduces Vaccine Efficacy for SARS-CoV-2. bioRxiv [Preprint]. 2022 Oct 17:2022.10.15.512291. doi: 10.1101/2022.10.15.512291.

Logue J, Chakraborty AR, Johnson R, Goyal G, Rodas M, Taylor LJ, Baracco L, McGrath ME, Haupt R, Furlong BA, Soong M, Prabhala P, Horvath V, Carlson KE, Weston S, Ingber DE, DePamphilis ML, Frieman MB. PIKfyve-specific inhibitors restrict replication of multiple coronaviruses in vitro but not in a murine model of COVID-19. Commun Biol. 2022 Aug 12;5(1):808. doi: 10.1038/s42003-022-03766-2.

Nanishi E, Borriello F, O'Meara TR, McGrath ME, Saito Y, Haupt RE, Seo HS, van Haren SD, Cavazzoni CB, Brook B, Barman S, Chen J, Diray-Arce J, Doss-Gollin S, De Leon M, Prevost-Reilly A, Chew K, Menon M, Song K, Xu AZ, Caradonna TM, Feldman J, Hauser BM, Schmidt AG, Sherman AC, Baden LR, Ernst RK, Dillen C, Weston SM, Johnson RM, Hammond HL, Mayer R, Burke A, Bottazzi ME, Hotez PJ, Strych U, Chang A, Yu J, Sage PT, Barouch DH, Dhe-Paganon S, Zanoni I, Ozonoff A, Frieman MB, Levy O, Dowling DJ. An aluminum hydroxide:CpG adjuvant enhances protection elicited by a SARS-CoV-2 receptor binding domain vaccine in aged mice. Sci Transl Med. 2022 Jan 26;14(629):eabj5305. doi: 10.1126/scitranslmed.abj5305.

McGrath ME, Xue Y, Dillen C, Oldfield L, Assad-Garcia N, Zaveri J, Singh N, Baracco L, Taylor LJ, Vashee S, Frieman MB. SARS-CoV-2 variant spike and accessory gene mutations alter pathogenesis. Proc Natl Acad Sci U S A. 2022 Sep 13;119(37):e2204717119. doi: 10.1073/pnas.2204717119.

Nanishi E, McGrath ME, O'Meara TR, Barman S, Yu J, Wan H, Dillen CA, Menon M, Seo HS, Song K, Xu AZ, Sebastian L, Brook B, Bosco AN, Borriello F, Ernst RK, Barouch DH, Dhe-Paganon S, Levy O, Frieman MB, Dowling DJ. mRNA booster vaccination protects aged mice against the SARS-CoV-2 Omicron variant. Commun Biol. 2022 Aug 6;5(1):790. doi: 10.1038/s42003-022-03765-3.

Sheng Y, Vinjamuri A, Alvarez MRS, Xie Y, McGrath M, Chen S, Barboza M, Frieman M, Lebrilla CB. Host Cell Glycocalyx Remodeling Reveals SARS-CoV-2 Spike Protein Glycomic Binding Sites. Front Mol Biosci. 2022 Mar 14;9:799703. doi: 10.3389/fmolb.2022.799703.

Rodriguez-Rodriguez BA, Ciabattoni GO, Valero-Jimenez AM, Crosse KM, Schinlever AR, Galvan JJR, Duerr R, Yeung ST, McGrath ME, Loomis C, Khanna KM, Desvignes L, Frieman MF, Ortigoza MB, Dittmann M. A neonatal mouse model characterizes transmissibility of SARS-CoV-2 variants and reveals a role for ORF8. bioRxiv [Preprint]. 2022 Oct 24:2022.10.04.510658. doi: 10.1101/2022.10.04.510658.

Meara TR, Nanishi E, McGrath ME, Barman S, Dong D, Dillen C, Menon M, Seo HS, Dhe-Paganon S, Ernst RK, Levy O, Frieman MB, Dowling DJ. Reduced SARS-CoV-2 mRNA vaccine immunogenicity and protection in mice with diet-induced obesity and insulin resistance. bioRxiv [Preprint]. 2022 Dec 7:2022.12.07.519460. doi: 10.1101/2022.12.07.519460.

Brook B, Fatou B, Checkervarty A, Barman S, Sweitzer C, Bosco AN, Sherman A, Baden LR, Morrocchi E, Sanchez-Schmitz G, Palma P, Nanishi E, O'Meara T, McGrath M, Frieman M, Soni D, van Haren S, Ozonoff A, Diray-Arce J, Steen H, Dowling D, Levy O. The mRNA vaccine BNT162b2 demonstrates impaired TH1 immunogenicity in human elders in vitro and aged mice in vivo. Res Sq [Preprint]. 2022 Dec 21:rs.3.rs-2395118. doi: 10.21203/rs.3.rs-2395118/v1.

Narasimhan S, Rajeevan N, Graham M, Wu MJ, DePonte K, Marion S, Masson O, O'Neal AJ, Pedra JHF, Sonenshine DE, Fikrig E. Tick transmission of Borrelia burgdorferi to the murine host is not influenced by environmentally acquired midgut microbiota. Microbiome. 2022 Oct 17;10(1):173. doi: 10.1186/s40168-022-01378-w.

Riley Risteen

Verhoeve VI, Fauntleroy TD, Risteen RG, Driscoll TP, Gillespie JJ. Cryptic Genes for Interbacterial Antagonism Distinguish Rickettsia Species Infecting Blacklegged Ticks From Other Rickettsia Pathogens. Front Cell Infect Microbiol. 2022 May 3;12:880813. doi: 10.3389/fcimb.2022.880813.

Kieran Tebben

Tebben K, Dia A, Serre D. Determination of the Stage Composition of Plasmodium Infections from Bulk Gene Expression Data. mSystems. 2022 Aug 30;7(4):e0025822. doi: 10.1128/msystems.00258-22.

Michael Sikorski

Hoffman SA, Desai SN, Sikorski MJ, Fatupaito G, Tupua S, Thomsen RE, Rambocus S, Nimarota-Brown S, Punimata LL, Sialeipata M, Tuilagi CF, Han J, Robins-Browne RM, Naseri TK, Levine MM. Point-of-Care Ultrasound by Nonexpert Operators Demonstrates High Sensitivity and Specificity in Detecting Gallstones: Data from the Samoa Typhoid Fever Control Program. Am J Trop Med Hyg. 2022 Jan 10;106(3):798-804. doi: 10.4269/ajtmh.21-0973.

Ellis Tibbs

Tibbs E, Cao X. Murine myeloid derived suppressor cells possess a range of suppressive mechanisms-Granzyme B is not among them. Cancer Immunol Immunother. 2022 Feb 7. doi: 10.1007/s00262-022-03162-z.

Back to top

Neuroscience

Sydney Ashton-Cromwell

VanRyzin JW, Marquardt AE, Argue KJ, Vecchiarelli HA, Ashton SE, Arambula SE, Hill MN, McCarthy MM. Microglial Phagocytosis of Newborn Cells Is Induced by Endocannabinoids and Sculpts Sex Differences in Juvenile Rat Social Play. Neuron. 2022 Apr 6;110(7):1271. doi: 10.1016/j.neuron.2022.03.013.

Garrett Bunce

McKeon PN, Bunce GW, Patton MH, Chen R, Mathur BN. Cortical control of striatal fast-spiking interneuron synchrony. J Physiol. 2022 May;600(9):2189-2202. doi: 10.1113/JP282850.

Altas B, Romanowski AJ, Bunce GW, Poulopoulos A. Neuronal mTOR Outposts: Implications for Translation, Signaling, and Plasticity. Front Cell Neurosci. 2022 Apr 7;16:853634. doi: 10.3389/fncel.2022.853634.

Soad Elziny

Iffland PH, Everett ME, Cobb-Pitstick KM, Bowser LE, Barnes AE, Babus JK, Romanowski AJ, Baybis M, Elziny S, Puffenberger EG, Gonzaga-Jauregui C, Poulopoulos A, Carson VJ, Crino PB. NPRL3 loss alters neuronal morphology, mTOR localization, cortical lamination and seizure threshold. Brain. 2022 Nov 21;145(11):3872-3885. doi: 10.1093/brain/awac044.

Daniela Franco

Siemsen BM, Franco D, Lobo MK. Corticostriatal contributions to dysregulated motivated behaviors in stress, depression, and substance use disorders. Neurosci Res. 2022 Dec 21:S0168-0102(22)00304-2. doi: 10.1016/j.neures.2022.12.014.

Franco D, Wulff AB, Lobo MK, Fox ME. Chronic Physical and Vicarious Psychosocial Stress Alter Fentanyl Consumption and Nucleus Accumbens Rho GTPases in Male and Female C57BL/6 Mice. Front Behav Neurosci. 2022 Feb 10;16:821080. doi: 10.3389/fnbeh.2022.821080.

Fox ME, Wulff AB, Franco D, Choi EY, Calarco CA, Engeln M, Turner MD, Chandra R, Rhodes VM, Thompson SM, Ament SA, Lobo MK. Adaptations in Nucleus Accumbens Neuron Subtypes Mediate Negative Affective Behaviors in Fentanyl Abstinence. Biol Psychiatry. 2022 Aug 30:S0006-3223(22)01551-7. doi: 10.1016/j.biopsych.2022.08.023.

Pagliusi M Jr, Franco D, Cole S, Morais-Silva G, Chandra R, Fox ME, Iñiguez SD, Sartori CR, Lobo MK. The BDNF-TrkB Pathway Acts Through Nucleus Accumbens D2 Expressing Neurons to Mediate Stress Susceptible Outcomes. Front Psychiatry. 2022 Jun 2;13:854494. doi: 10.3389/fpsyt.2022.854494.

Maxwell Madden

Doss MK, Madden MB, Gaddis A, Nebel MB, Griffiths RR, Mathur BN, Barrett FS. Models of psychedelic drug action: modulation of cortical-subcortical circuits. Brain. 2022 Apr 18;145(2):441-456. doi: 10.1093/brain/awab406.

Madden MB, Stewart BW, White MG, Krimmel SR, Qadir H, Barrett FS, Seminowicz DA, Mathur BN. A role for the claustrum in cognitive control. Trends Cogn Sci. 2022 Dec;26(12):1133-1152. doi: 10.1016/j.tics.2022.09.006.

Miriam Menken

Isaiah A, Ernst TM, Liang H, Ryan M, Cunningham E, Rodriguez PJ, Menken M, Kaschak D, Guihen C, Reeves G, Lever N, Edwards SM, Chang L. Associations between socioeconomic gradients and racial disparities in preadolescent brain outcomes. Pediatr Res. 2022 Dec 1. doi: 10.1038/s41390-022-02399-9

Menken MS, Isaiah A, Liang H, Rivera PR, Cloak CC, Reeves G, Lever NA, Chang L. Peer victimization (bullying) on mental health, behavioral problems, cognition, and academic performance in preadolescent children in the ABCD Study. Front Psychol. 2022 Sep 26;13:925727. doi: 10.3389/fpsyg.2022.925727.

Kristen Montgomery

Cole AB, Montgomery K, Bale TL, Thompson SM. What the hippocampus tells the HPA axis: Hippocampal output attenuates acute stress responses via disynaptic inhibition of CRF+ PVN neurons. Neurobiol Stress. 2022 Aug 5;20:100473. doi: 10.1016/j.ynstr.2022.100473.

Mitchell Moyer

Ksendzovsky A, Bachani M, Altshuler M, Walbridge S, Mortazavi A, Moyer M, Chen C, Fayed I, Steiner J, Edwards N, Inati SK, Jahanipour J, Maric D, Heiss JD, Kapur J, Zaghloul KA. Chronic neuronal activation leads to elevated lactate dehydrogenase A through the AMP-activated protein kinase/hypoxia-inducible factor-1α hypoxia pathway. Brain Commun. 2022 Dec 1;5(1):fcac298. doi: 10.1093/braincomms/fcac298.

Houman Qadir

Madden MB, Stewart BW, White MG, Krimmel SR, Qadir H, Barrett FS, Seminowicz DA, Mathur BN. A role for the claustrum in cognitive control. Trends Cogn Sci. 2022 Dec;26(12):1133-1152. doi: 10.1016/j.tics.2022.09.006.

Qadir H, Stewart BW, VanRyzin JW, Wu Q, Chen S, Seminowicz DA, Mathur BN. The mouse claustrum synaptically connects cortical network motifs. Cell Rep. 2022 Dec 20;41(12):111860. doi: 10.1016/j.celrep.2022.111860.

Engeln M, Fox ME, Chandra R, Choi EY, Nam H, Qadir H, Thomas SS, Rhodes VM, Turner MD, Herman RJ, Calarco CA, Lobo MK. Transcriptome profiling of the ventral pallidum reveals a role for pallido-thalamic neurons in cocaine reward. Mol Psychiatry. 2022 Oct;27(10):3980-3991. doi: 10.1038/s41380-022-01668-7.

Colin Robertson

Hariharan A, Robertson CD, Garcia DCG, Longden TA. Brain capillary pericytes are metabolic sentinels that control blood flow through a KATP channel-dependent energy switch. Cell Rep. 2022 Dec 27;41(13):111872. doi: 10.1016/j.celrep.2022.111872.

Pedro Rodriguez Rivera

Menken MS, Isaiah A, Liang H, Rivera PR, Cloak CC, Reeves G, Lever NA, Chang L. Peer victimization (bullying) on mental health, behavioral problems, cognition, and academic performance in preadolescent children in the ABCD Study. Front Psychol. 2022 Sep 26;13:925727. doi: 10.3389/fpsyg.2022.925727.

Meghann Ryan

Isaiah A, Ernst TM, Liang H, Ryan M, Cunningham E, Rodriguez PJ, Menken M, Kaschak D, Guihen C, Reeves G, Lever N, Edwards SM, Chang L. Associations between socioeconomic gradients and racial disparities in preadolescent brain outcomes. Pediatr Res. 2022 Dec 1. doi: 10.1038/s41390-022-02399-9.

Brent Stewart

Georgiou P, Zanos P, Mou TM, An X, Gerhard DM, Dryanovski DI, Potter LE, Highland JN, Jenne CE, Stewart BW, Pultorak KJ, Yuan P, Powels CF, Lovett J, Pereira EFR, Clark SM, Tonelli LH, Moaddel R, Zarate CA Jr, Duman RS, Thompson SM, Gould TD. Experimenters' sex modulates mouse behaviors and neural responses to ketamine via corticotropin releasing factor. Nat Neurosci. 2022 Sep;25(9):1191-1200. doi: 10.1038/s41593-022-01146-x.

Madden MB, Stewart BW, White MG, Krimmel SR, Qadir H, Barrett FS, Seminowicz DA, Mathur BN. A role for the claustrum in cognitive control. Trends Cogn Sci. 2022 Dec;26(12):1133-1152. doi: 10.1016/j.tics.2022.09.006.

Qadir H, Stewart BW, VanRyzin JW, Wu Q, Chen S, Seminowicz DA, Mathur BN. The mouse claustrum synaptically connects cortical network motifs. Cell Rep. 2022 Dec 20;41(12):111860. doi: 10.1016/j.celrep.2022.111860.

Andreas Wulff

Fox ME, Wulff AB, Franco D, Choi EY, Calarco CA, Engeln M, Turner MD, Chandra R, Rhodes VM, Thompson SM, Ament SA, Lobo MK. Adaptations in Nucleus Accumbens Neuron Subtypes Mediate Negative Affective Behaviors in Fentanyl Abstinence. Biol Psychiatry. 2022 Aug 30:S0006-3223(22)01551-7. doi: 10.1016/j.biopsych.2022.08.023.

Franco D, Wulff AB, Lobo MK, Fox ME. Chronic Physical and Vicarious Psychosocial Stress Alter Fentanyl Consumption and Nucleus Accumbens Rho GTPases in Male and Female C57BL/6 Mice. Front Behav Neurosci. 2022 Feb 10;16:821080. doi: 10.3389/fnbeh.2022.821080.

Naibo Zhang

Bordt EA, Zhang N, Waddell J, Polster BM. The Non-Specific Drp1 Inhibitor Mdivi-1 Has Modest Biochemical Antioxidant Activity. Antioxidants (Basel). 2022 Feb 24;11(3):450. doi: 10.3390/antiox11030450.

Back to top.

Physical Rehabilitation Science

Nesreen Alissa

Jeon W, Whitall J, Alissa N, Westlake K. Age-related differences in stepping stability following a sudden gait perturbation are associated with lower limb eccentric control of the perturbed limb. Exp Gerontol. 2022 Oct 1;167:111917. doi: 10.1016/j.exger.2022.111917.

Kathleen Dondero

Landers-Ramos RQ, Dondero K, Nelson C, Ranadive SM, Prior SJ, Addison O. Muscle thickness and inflammation during a 50km ultramarathon in recreational runners. PLoS One. 2022 Sep 1;17(9):e0273510. doi: 10.1371/journal.pone.0273510.

Landers-Ramos RQ, Lawal I, Imery I, Siok D, Addison O, Zabriskie HA, Dondero K, Dobrosielski DA. High-intensity functional exercise does not cause persistent elevations in augmentation index in young men and women. Appl Physiol Nutr Metab. 2022 Sep 1;47(9):963-972. doi: 10.1139/apnm-2022-0081.

Dondero KR, Falvey JR, Beamer BA, Addison O. Geriatric Vulnerabilities Among Obese Older Adults With and Without Sarcopenia: Findings From a Nationally Representative Cohort Study. J Geriatr Phys Ther. 2022 Aug 18. doi: 10.1519/JPT.0000000000000358.

Simon Ho

Ho S, Rock K, Addison O, Marchese V. Relationships between diaphragm ultrasound, spirometry, and respiratory mouth pressures in children. Respir Physiol Neurobiol. 2022 Nov;305:103950. doi: 10.1016/j.resp.2022.103950.

Ho S, Culligan M, Friedberg J, Goloubeva O, Marchese V. Examining the impact of physical function performance in predicting patient outcomes after lung-sparing surgery for malignant pleural mesothelioma. Disabil Rehabil. 2022 Nov;44(22):6676-6683. doi: 10.1080/09638288.2021.1970256.

Sarah Margerison

Margerison SM, Westlake KP, Seminowicz DA. Beyond pain in the brain: A clinician's guide to interpreting the spinal cord's role in the pain experience. Musculoskelet Sci Pract. 2022 Dec;62:102664. doi: 10.1016/j.msksp.2022.102664.

Kelly Rock

Marchese V, Rock K, Harpold A, Salazar A, Williams M, Shipper AG. Physical Impairment and Function in Children and Adolescents With Sickle Cell Disease: A Systematic Review. Arch Phys Med Rehabil. 2022 Jun;103(6):1144-1167.e2. doi: 10.1016/j.apmr.2021.08.022.

Ho S, Rock K, Addison O, Marchese V. Relationships between diaphragm ultrasound, spirometry, and respiratory mouth pressures in children. Respir Physiol Neurobiol. 2022 Nov;305:103950. doi: 10.1016/j.resp.2022.103950.

Marchese V, Rock K, York T, Ruble K, Gray VL. The Efficacy of Targeted Exercise on Gross Motor and Neuromuscular Performance in Survivors of Childhood Leukemia: A Pilot Study. Front Pediatr. 2022 May 11;10:891650. doi: 10.3389/fped.2022.891650.

Lanza MB, Rock K, Marchese V, Gray VL, Addison O. Ultrasound measures of muscle thickness and subcutaneous tissue from the hip abductors: Inter- and intra-rater reliability. Musculoskelet Sci Pract. 2022 Dec;62:102612. doi: 10.1016/j.msksp.2022.102612.

Rock K, Addison O, Gray VL, Nelson CM, Henshaw RM, York T, Ruble K, Marchese V. Quantifying muscle strength, size, and neuromuscular activation in adolescent and young adult survivors of musculoskeletal sarcoma: Identifying correlates and responses to functional strengthening. Knee. 2022 Dec 16;40:270-282. doi: 10.1016/j.knee.2022.11.024.

Back to top