2023 Publications
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Biochemistry & Molecular Biology
Molecular Microbiology & Immunology
Physical Rehabilitation Science
Biochemistry & Molecular Biology
Emmanuel Asiedu
Kratzmeier C, Singh S, Asiedu EB, Webb TJ. Current Developments in the Preclinical and Clinical use of Natural Killer T cells. BioDrugs. 2023 Jan;37(1):57-71. doi: 10.1007/s40259-022-00572-4.
Hugo Bibollet
Bibollet H, Kramer A, Bannister RA, Hernández-Ochoa EO. Advances in CaV1.1 gating: New insights into permeation and voltage-sensing mechanisms. Channels (Austin). 2023 Dec;17(1):2167569. doi: 10.1080/19336950.2023.2167569.
Xi Chen
Chen X, Adhikary G, Ma E, Newland JJ, Naselsky W, Xu W, Eckert RL. Sulforaphane inhibits CD44v6/YAP1/TEAD signaling to suppress the cancer phenotype. Mol Carcinog. 2023 Feb;62(2):236-248. doi: 10.1002/mc.23479.
Chen X, Adhikary G, Newland JJ, Xu W, Ma E, Naselsky W, Eckert RL. The transglutaminase 2 cancer cell survival factor maintains mTOR activity to drive an aggressive cancer phenotype. Mol Carcinog. 2023 Jan;62(1):90-100. doi: 10.1002/mc.23446.
Eric Choi
Choi EY, Franco D, Stapf CA, Gordin M, Chow A, Cover KK, Chandra R, Lobo MK. Inducible CRISPR Epigenome Systems Mimic Cocaine Induced Bidirectional Regulation of Nab2 and Egr3. J Neurosci. 2023 Feb 27:JN-RM-1802-22. doi: 10.1523/JNEUROSCI.1802-22.2022.
Nivedita Hegdekar
Hegdekar N, Sarkar C, Bustos S, Ritzel RM, Hanscom M, Ravishankar P, Philkana D, Wu J, Loane DJ, Lipinski MM. Inhibition of autophagy in microglia and macrophages exacerbates innate immune responses and worsens brain injury outcomes. Autophagy. 2023 Jan 18:1-19. doi: 10.1080/15548627.2023.2167689.
Sudeep Khadka
Jeon HY, Pornour M, Ryu H, Khadka S, Xu R, Jang J, Li D, Chen H, Hussain A, Fazli L, Gleave M, Dong X, Huang F, Wang Q, Barbieri C, Qi J. SMAD3 promotes expression and activity of the androgen receptor in prostate cancer. Nucleic Acids Res. 2023 Feb 2:gkad043. doi: 10.1093/nar/gkad043.
Hardler Servius
Pidugu LS, Servius HW, Sevdalis SE, Cook ME, Varney KM, Pozharski E, Drohat AC. Characterizing inhibitors of human AP endonuclease 1. PLoS One. 2023 Jan 18;18(1):e0280526. doi: 10.1371/journal.pone.0280526.
Servius HW, Pidugu LS, Sherman ME, Drohat AC. Rapid excision of oxidized adenine by human thymine DNA glycosylase. J Biol Chem. 2023 Jan;299(1):102756. doi: 10.1016/j.jbc.2022.102756.
Spiridon Sevdalis
Pidugu LS, Servius HW, Sevdalis SE, Cook ME, Varney KM, Pozharski E, Drohat AC. Characterizing inhibitors of human AP endonuclease 1. PLoS One. 2023 Jan 18;18(1):e0280526. doi: 10.1371/journal.pone.0280526.
Matthew Sherman
Servius HW, Pidugu LS, Sherman ME, Drohat AC. Rapid excision of oxidized adenine by human thymine DNA glycosylase. J Biol Chem. 2023 Jan;299(1):102756. doi: 10.1016/j.jbc.2022.102756.
Megan Stemberger
Chang KT, Thompson KN, Pratt SJP, Ju JA, Lee RM, Mathias TJ, Mull ML, Annis DA, Ory EC, Stemberger MB, Vitolo MI, Martin SS. Elevation of Cytoplasmic Calcium Suppresses Microtentacle Formation and Function in Breast Tumor Cells. Cancers (Basel). 2023 Jan 31;15(3):884. doi: 10.3390/cancers15030884.
Saif Yasin
White JA, Wu F, Yasin S, Moskovljevic M, Varriale J, Dragoni F, Camilo Contreras A, Duan J, Zheng MY, Tadzong NF, Patel HB, Quiambao JMC, Rhodehouse K, Zhang H, Lai J, Beg SA, Delannoy M, Kilcrease C, Hoffmann CJ, Poulin S, Chano F, Tremblay C, Cherian J, Barditch-Crovo P, Chida N, Moore RD, Summers MF, Siliciano RF, Siliciano JD, Simonetti FR. Clonally expanded HIV-1 proviruses with 5'-Leader defects can give rise to nonsuppressible residual viremia. J Clin Invest. 2023 Jan 5:e165245. doi: 10.1172/JCI165245.
Epidemiology & Human Genetics
David Annis
Chang KT, Thompson KN, Pratt SJP, Ju JA, Lee RM, Mathias TJ, Mull ML, Annis DA, Ory EC, Stemberger MB, Vitolo MI, Martin SS. Elevation of Cytoplasmic Calcium Suppresses Microtentacle Formation and Function in Breast Tumor Cells. Cancers (Basel). 2023 Jan 31;15(3):884. doi: 10.3390/cancers15030884.
Matthew Adams
Lyke KE, Berry AA, Mason K, Idris AH, O'Callahan M, Happe M, Strom L, Berkowitz NM, Guech M, Hu Z, Castro M, Basappa M, Wang L, Low K, Holman LA, Mendoza F, Gordon IJ, Plummer SH, Trofymenko O, Strauss KS, Joshi S, Shrestha B, Adams M, Chagas AC, Murphy JR, Stein J, Hickman S, McDougal A, Lin B, Narpala SR, Vazquez S, Serebryannyy L, McDermott A, Gaudinski MR, Capparelli EV, Coates EE, Wu RL, Ledgerwood JE, Dropulic LK, Seder RA; VRC 612 Part C Study Team. Low-dose intravenous and subcutaneous CIS43LS monoclonal antibody for protection against malaria (VRC 612 Part C): a phase 1, adaptive trial. Lancet Infect Dis. 2023 Jan 25:S1473-3099(22)00793-9. doi: 10.1016/S1473-3099(22)00793-9.
Nyangulu W, Mungwira RG, Divala TH, Nampota-Nkomba N, Nyirenda OM, Buchwald AG, Miller J, Earland DE, Adams M, Plowe CV, Taylor TE, Mallewa JE, van Oosterhout JJ, Parikh S, Laurens MB, Laufer MK; TSCQ Study Team. Artemether-lumefantrine efficacy among adults on antiretroviral therapy in Malawi. Malar J. 2023 Jan 27;22(1):32. doi: 10.1186/s12936-023-04466-w.
Miriam Doyinsola Bailey
Bailey MD, Gambert S, Gruber-Baldini A, Guralnik J, Kozar R, Qato DM, Shardell M, Albrecht JS. Traumatic Brain Injury and Risk of Long-Term Nursing Home Entry among Older Adults: An Analysis of Medicare Administrative Claims Data. J Neurotrauma. 2023 Jan;40(1-2):86-93. doi: 10.1089/neu.2022.0003.
Jonathan Lawton
Aliyu GG, Lawton JG, Mitchell AB, Abimiku AG, Jelpe T, Bassey O, Riedel DJ, Swaminathan M, Chang JC, DeVos JR, Patel H, Charurat ME, Stafford KA; on behalf on the NAIIS Study Group. Prevalence of HIV drug resistance in Nigeria: results from a cross-sectional, population-based survey of Nigerian adults with unsuppressed viral load. AIDS. 2023 Feb 1;37(2):333-339. doi: 10.1097/QAD.0000000000003413.
Lawton J, Lavoie MC, Bashorun A, Dalhatu I, Jahun I, Agbakwuru C, Boyd M, Stafford K, Swaminathan M, Aliyu G, Charurat M; NAIIS Study Group. Individual and household factors associated with non-disclosure of positive HIV status in a population-based HIV serosurvey. AIDS. 2023 Jan 1;37(1):191-196. doi: 10.1097/QAD.0000000000003404.
Richard Smith
Onyedibe KI, Nemeth AM, Dayal N, Smith RD, Lamptey J, Ernst RK, Melander RJ, Melander C, Sintim HO. Re-sensitization of Multidrug-Resistant and Colistin-Resistant Gram-Negative Bacteria to Colistin by Povarov/Doebner-Derived Compounds. ACS Infect Dis. 2023 Jan 18. doi: 10.1021/acsinfecdis.2c00417.
Christina Stennett
Tuddenham S, Gajer P, Burke AE, Murphy C, Klein SL, Stennett CA, Wilgus B, Ravel J, Ghanem KG, Brotman RM. Lactobacillus-dominance and rapid stabilization of vaginal microbiota in combined oral contraceptive pill users examined through a longitudinal cohort study with frequent vaginal sampling over two years. EBioMedicine. 2023 Jan;87:104407. doi: 10.1016/j.ebiom.2022.104407.
Emily Stucke
Tebben K, Yirampo S, Coulibaly D, Koné AK, Laurens MB, Stucke EM, Dembélé A, Tolo Y, Traoré K, Niangaly A, Berry AA, Kouriba B, Plowe CV, Doumbo OK, Lyke KE, Takala-Harrison S, Thera MA, Travassos MA, Serre D. Malian children infected with Plasmodium ovale and Plasmodium falciparum display very similar gene expression profiles. PLoS Negl Trop Dis. 2023 Jan 25;17(1):e0010802. doi: 10.1371/journal.pntd.0010802.
Zhenyao Ye
Bruce HA, Kochunov P, Kvarta MD, Goldwaser EL, Chiappelli J, Schwartz A, Lightner S, Endres J, Yuen A, Ma Y, Van der Vaart A, Hatch KS, Gao S, Ye Z, Wu Q, Chen S, Mitchell BD, Hong LE. Frontal white matter association with sleep quality and the role of stress. J Sleep Res. 2023 Feb;32(1):e13669. doi: 10.1111/jsr.13669.
Gerontology
Rachel McPherson
Molecular Medicine
Christine Carney
Carney CP, Kapur A, Anastasiadis P, Ritzel RM, Chen C, Woodworth GF, Winkles JA, Kim AJ. Fn14-Directed DART Nanoparticles Selectively Target Neoplastic Cells in Preclinical Models of Triple-Negative Breast Cancer Brain Metastasis. Mol Pharm. 2023 Jan 2;20(1):314-330. doi: 10.1021/acs.molpharmaceut.2c00663.
Katarina Chang
Chang KT, Thompson KN, Pratt SJP, Ju JA, Lee RM, Mathias TJ, Mull ML, Annis DA, Ory EC, Stemberger MB, Vitolo MI, Martin SS. Elevation of Cytoplasmic Calcium Suppresses Microtentacle Formation and Function in Breast Tumor Cells. Cancers (Basel). 2023 Jan 31;15(3):884. doi: 10.3390/cancers15030884.
Kevin Herold
Herold KG, Hussey JW, Dick IE. CACNA1C-Related Channelopathies. Handb Exp Pharmacol. 2023 Jan 5. doi: 10.1007/164_2022_624.
Julia Ju
Chang KT, Thompson KN, Pratt SJP, Ju JA, Lee RM, Mathias TJ, Mull ML, Annis DA, Ory EC, Stemberger MB, Vitolo MI, Martin SS. Elevation of Cytoplasmic Calcium Suppresses Microtentacle Formation and Function in Breast Tumor Cells. Cancers (Basel). 2023 Jan 31;15(3):884. doi: 10.3390/cancers15030884.
Trevor Mathias
Chang KT, Thompson KN, Pratt SJP, Ju JA, Lee RM, Mathias TJ, Mull ML, Annis DA, Ory EC, Stemberger MB, Vitolo MI, Martin SS. Elevation of Cytoplasmic Calcium Suppresses Microtentacle Formation and Function in Breast Tumor Cells. Cancers (Basel). 2023 Jan 31;15(3):884. doi: 10.3390/cancers15030884.
Makenzy Mull
Chang KT, Thompson KN, Pratt SJP, Ju JA, Lee RM, Mathias TJ, Mull ML, Annis DA, Ory EC, Stemberger MB, Vitolo MI, Martin SS. Elevation of Cytoplasmic Calcium Suppresses Microtentacle Formation and Function in Breast Tumor Cells. Cancers (Basel). 2023 Jan 31;15(3):884. doi: 10.3390/cancers15030884.
Stephen Pratt
Chang KT, Thompson KN, Pratt SJP, Ju JA, Lee RM, Mathias TJ, Mull ML, Annis DA, Ory EC, Stemberger MB, Vitolo MI, Martin SS. Elevation of Cytoplasmic Calcium Suppresses Microtentacle Formation and Function in Breast Tumor Cells. Cancers (Basel). 2023 Jan 31;15(3):884. doi: 10.3390/cancers15030884.
Mashhood Wani
Zhang JM, Au DT, Sawada H, Franklin MK, Moorleghen JJ, Howatt DA, Wang P, Aicher BO, Hampton B, Migliorini M, Ni F, Mullick AE, Wani MM, Ucuzian AA, Lu HS, Muratoglu SC, Daugherty A, Strickland DK. LRP1 protects against excessive superior mesenteric artery remodeling by modulating angiotensin II-mediated signaling. JCI Insight. 2023 Jan 24;8(2):e164751. doi: 10.1172/jci.insight.164751.
Molecular Microbiology and Immunology
Corbin Goerlich
Goerlich CE, Griffith BP, Shah A, Treffalls JA, Zhang T, Lewis B, Tatarov I, Hershfeld A, Sentz F, Braileanu G, Ayares D, Singh AK, Mohiuddin MM. A Standardized Approach to Orthotopic (Life-supporting) Porcine Cardiac Xenotransplantation in a Nonhuman Primate Model. Transplantation. 2023 Jan 23. doi: 10.1097/TP.0000000000004508.
Strauss ER, Odonkor PN, Williams B, Choi S, Mueller J, Taylor B, Shah A, Goerlich CE, Mohiuddin MM, Griffith BP. Intraoperative Management of an Orthotopic Porcine-to-Human Cardiac Xenotransplant. Ann Thorac Surg. 2023 Jan 6:S0003-4975(23)00007-3. doi: 10.1016/j.athoracsur.2023.01.001.
Mohiuddin MM, Singh AK, Goerlich CE. Preclinical rationale and current pathways to support the first human clinical trials in cardiac xenotransplantation. Hum Immunol. 2023 Jan;84(1):34-42. doi: 10.1016/j.humimm.2022.07.001.
Goerlich CE, Griffith B, Hanna P, Hong SN, Ayares D, Singh AK, Mohiuddin MM. The growth of xenotransplanted hearts can be reduced with growth hormone receptor knockout pig donors. J Thorac Cardiovasc Surg. 2023 Feb;165(2):e69-e81. doi: 10.1016/j.jtcvs.2021.07.051.
Hanover Matz
Chen WH, Hajduczki A, Martinez EJ, Bai H, Matz H, Hill TM, Lewitus E, Chang WC, Dawit L, Peterson CE, Rees PA, Ajayi AB, Golub ES, Swafford I, Dussupt V, David S, Mayer SV, Soman S, Kuklis C, Corbitt C, King J, Choe M, Sankhala RS, Thomas PV, Zemil M, Wieczorek L, Hart T, Duso D, Kummer L, Yan L, Sterling SL, Laing ED, Broder CC, Williams JK, Davidson E, Doranz BJ, Krebs SJ, Polonis VR, Paquin-Proulx D, Rolland M, Reiley WW, Gromowski GD, Modjarrad K, Dooley H, Joyce MG. Shark nanobodies with potent SARS-CoV-2 neutralizing activity and broad sarbecovirus reactivity. Nat Commun. 2023 Feb 3;14(1):580. doi: 10.1038/s41467-023-36106-x.
Thomas Hill
Chen WH, Hajduczki A, Martinez EJ, Bai H, Matz H, Hill TM, Lewitus E, Chang WC, Dawit L, Peterson CE, Rees PA, Ajayi AB, Golub ES, Swafford I, Dussupt V, David S, Mayer SV, Soman S, Kuklis C, Corbitt C, King J, Choe M, Sankhala RS, Thomas PV, Zemil M, Wieczorek L, Hart T, Duso D, Kummer L, Yan L, Sterling SL, Laing ED, Broder CC, Williams JK, Davidson E, Doranz BJ, Krebs SJ, Polonis VR, Paquin-Proulx D, Rolland M, Reiley WW, Gromowski GD, Modjarrad K, Dooley H, Joyce MG. Shark nanobodies with potent SARS-CoV-2 neutralizing activity and broad sarbecovirus reactivity. Nat Commun. 2023 Feb 3;14(1):580. doi: 10.1038/s41467-023-36106-x.
Christina Kratzmeier
Kratzmeier C, Singh S, Asiedu EB, Webb TJ. Current Developments in the Preclinical and Clinical use of Natural Killer T cells. BioDrugs. 2023 Jan;37(1):57-71. doi: 10.1007/s40259-022-00572-4.
Jernelle Miller
Nyangulu W, Mungwira RG, Divala TH, Nampota-Nkomba N, Nyirenda OM, Buchwald AG, Miller J, Earland DE, Adams M, Plowe CV, Taylor TE, Mallewa JE, van Oosterhout JJ, Parikh S, Laurens MB, Laufer MK; TSCQ Study Team. Artemether-lumefantrine efficacy among adults on antiretroviral therapy in Malawi. Malar J. 2023 Jan 27;22(1):32. doi: 10.1186/s12936-023-04466-w.
Franklin Ning
Green DS, Ning F, Duemler A, Myers TG, Trewhitt K, Ekwede I, McCoy A, Houston N, Lee JM, Lipkowitz S, Zimmer A, Pavelova M, Villanueva EN, Smith L, Blakely A, Casablanca Y, Highfill SL, Stroncek DF, Collins-Johnson N, Panch S, Procter J, Pham C, Korrapati S, Holland SM, Rosen LB, Nunes AT, Zoon KC, Cole CB, Annunziata CM. Intraperitoneal Monocytes plus IFNs as a Novel Cellular Immunotherapy for Ovarian Cancer: Mechanistic Characterization and Results from a Phase I Clinical Trial. Clin Cancer Res. 2023 Jan 17;29(2):349-363. doi: 10.1158/1078-0432.CCR-22-1893.
Kieran Tebben
Tebben K, Yirampo S, Coulibaly D, Koné AK, Laurens MB, Stucke EM, Dembélé A, Tolo Y, Traoré K, Niangaly A, Berry AA, Kouriba B, Plowe CV, Doumbo OK, Lyke KE, Takala-Harrison S, Thera MA, Travassos MA, Serre D. Malian children infected with Plasmodium ovale and Plasmodium falciparum display very similar gene expression profiles. PLoS Negl Trop Dis. 2023 Jan 25;17(1):e0010802. doi: 10.1371/journal.pntd.0010802.
Ellis Tibbs
Sajjan S, Tibbs E, Utz M, Rapoport AP, Yared J, Dahiya S, Cao X, Hardy N, Sunshine SB. Can Janus kinase inhibition improve ocular graft versus host disease? Ocul Surf. 2023 Jan 10;28:27-29. doi: 10.1016/j.jtos.2023.01.001.
Neuroscience
Andrew Furman
Chowdhury NS, Skippen P, Si E, Chiang AKI, Millard SK, Furman AJ, Chen S, Schabrun SM, Seminowicz DA. The reliability of two prospective cortical biomarkers for pain: EEG peak alpha frequency and TMS corticomotor excitability. J Neurosci Methods. 2023 Feb 1;385:109766. doi: 10.1016/j.jneumeth.2022.109766.
Rachel Cundiff-O'Sullivan
Thomas S, Wang Y, Cundiff-O'Sullivan R, Massalee R, Colloca L. How negative and positive constructs and comorbid conditions contribute to disability in chronic orofacial pain. Eur J Pain. 2023 Jan;27(1):99-110. doi: 10.1002/ejp.2042.
Daniela Franco
Choi EY, Franco D, Stapf CA, Gordin M, Chow A, Cover KK, Chandra R, Lobo MK. Inducible CRISPR Epigenome Systems Mimic Cocaine Induced Bidirectional Regulation of Nab2 and Egr3. J Neurosci. 2023 Feb 27:JN-RM-1802-22. doi: 10.1523/JNEUROSCI.1802-22.2022.
John (Jack) Hussey
Hussey JW, Limpitikul WB, Dick IE. Calmodulin Mutations in Human Disease. Channels (Austin). 2023 Dec;17(1):2165278. doi: 10.1080/19336950.2023.2165278.
Herold KG, Hussey JW, Dick IE. CACNA1C-Related Channelopathies. Handb Exp Pharmacol. 2023 Jan 5. doi: 10.1007/164_2022_624.
Ashley Marquardt
Pickett LA, VanRyzin JW, Marquardt AE, McCarthy MM. Microglia phagocytosis mediates the volume and function of the rat sexually dimorphic nucleus of the preoptic area. Proc Natl Acad Sci U S A. 2023 Mar 7;120(10):e2212646120. doi: 10.1073/pnas.2212646120.
Lindsay Pickett
Pickett LA, VanRyzin JW, Marquardt AE, McCarthy MM. Microglia phagocytosis mediates the volume and function of the rat sexually dimorphic nucleus of the preoptic area. Proc Natl Acad Sci U S A. 2023 Mar 7;120(10):e2212646120. doi: 10.1073/pnas.2212646120.
Catherine Stapf
Choi EY, Franco D, Stapf CA, Gordin M, Chow A, Cover KK, Chandra R, Lobo MK. Inducible CRISPR Epigenome Systems Mimic Cocaine Induced Bidirectional Regulation of Nab2 and Egr3. J Neurosci. 2023 Feb 27:JN-RM-1802-22. doi: 10.1523/JNEUROSCI.1802-22.2022.
Physical Rehabilitation Science
Ruth Akinlosotu
Westlake K, Akinlosotu R, Udo J, Goldstein Shipper A, Waller SM, Whitall J. Some home-based self-managed rehabilitation interventions can improve arm activity after stroke: A systematic review and narrative synthesis. Front Neurol. 2023 Feb 2;14:1035256. doi: 10.3389/fneur.2023.1035256.
Kelly Rock
Rock K, Addison O, Gray VL, Henshaw RM, Ward C, Marchese V. Skeletal Muscle Measurements in Pediatric Hematology and Oncology: Essential Components to a Comprehensive Assessment. Children (Basel). 2023 Jan 5;10(1):114. doi: 10.3390/children10010114.
Rock K, Addison O, Gray VL, Nelson CM, Henshaw RM, York T, Ruble K, Marchese V. Quantifying muscle strength, size, and neuromuscular activation in adolescent and young adult survivors of musculoskeletal sarcoma: Identifying correlates and responses to functional strengthening. Knee. 2023 Jan;40:270-282. doi: 10.1016/j.knee.2022.11.024.