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Cancer Biology T-32 Training Grant

For additional information about the program or the application process, please contact:

Leanne Simington, MS
Grants and Contracts Coordinator
University of Maryland School of Medicine
Marlene and Stewart Greenebaum Cancer Center
MSTF, 3-57 W, 3-57J
410 706-8358
lsimington@som.umaryland.edu 

Toni M. Antalis, Ph.D.
Co-Director
Professor of Physiology,
University of Maryland School of Medicine
410 706-8222
tantalis@som.umaryland.edu 

Curt I. Civin, M.D.
Co-Director
Associate Dean for Research,
University of Maryland School of Medicine
410 706-1198/1181
ccivin@som.umaryland.edu 

Guidelines and Application 2020

The Cancer Biology T32 Training Program at the University of Maryland is a prestigious program designed to train predoctoral students and postdoctoral fellows in fundamental mechanisms of cancer biology at the molecular, cellular and organism levels. The program takes advantage of the multidisciplinary and highly interactive research environment within the University of Maryland Greenebaum Cancer Center and at the University of Maryland Baltimore campus to provide outstanding training in critical areas of basic and translational cancer research. A guiding philosophy is that Cancer Biology T32 training program must provide integrative activities that illuminate the inter-relatedness of basic cancer research and clinical medicine. Support for the program has been provided from a training grant from the NIH National Cancer Institute.

To be considered for a position on this training grant, the trainee should identify a faculty mentor and develop a research plan in conjunction with the mentor to be submitted with the application.

The award of a trainee slot on this grant is for a 1 year period, and is renewable by competitive application for a 2nd and possibly a 3rd year. Each year involves a competitive renewal with no greater assurance of funding for ongoing applicants than for new applicants. T32 supported trainees and mentors are strongly encouraged to apply for individual competitive fellowships or for other cancer research grant support during their 1st or 2nd year in the program. All predoctoral and postdoctoral fellows supported by the Cancer Biology T32 training program will be encouraged to participate in didactic components, interactive seminars and workshops, and professional development to appropriate to their background, in order to provide a solid foundation for a long term and successful career in cancer research.

The levels of funding support from the T32 grant are mandated by NIH guidelines (http://www.cancer.gov/researchandfunding/cancertraining/funding/T32). As appropriate, salary may be supplemented from other single or combined sources, such as research grants, professional fees, etc. Health insurance and support for travel is provided. For M.D. trainees, support from the T32 Training Program provides ‘protected time’ for immersion in the laboratory and it is required that patient care responsibilities will be limited to <10% effort (one half day per week), primarily to help complete long-term patient care experience necessary for their subspecialities and to maintain patient-care skills.

Qualifications for Trainee Slots:

• All appointments to this training grant are restricted to U.S. citizens and permanent residents.
• Applicants must be committed to cancer research.
Predoctoral applicants must be enrolled in GPILS (PhD or MD/PhD program) at the University of Maryland Baltimore. Students must have completed the required courses: GPLS 790 - Advanced Cancer Biology and GPLS 665 - Cancer Biology: From Basic Research to the Clinic.
Postdoctoral applicants must have completed doctoral level training (e.g. PhD, MD, MD/PhD, PharmD, DDS or equivalent). Evidence of scholarly productivity in the form of publications or planned publications is highly desirable. Post-doctoral trainees from Residency and Fellowship training programs (e.g. Radiation Oncology, Hematology/Oncology, and Oncology residents from OB-GYN, Otorhinolaryngology, Pathology, Pediatrics, Medicine or Surgery residency programs) are encouraged to apply.

 

Guidelines and Application 2020

Research by Faculty Members
Below is a list of faculty members along with the focus of their research. Click the name of a faculty member to see their Faculty Profile. Faculty profiles include detailed information and contact information. 

Adebamowo, Clement A., MD Sc.D 
The molecular biology of HPV associated cancer (cervical and head and neck cancer) and breast cancer

Antalis, Toni, PhD
Regulation of signaling pathways affecting cancer growth and metastasis, vascular biology, angiogenesis, and inflammation by serine proteases and their inhibitors

Baer, Maria, MD
Signaling pathways affecting drug resistance mechanisms in acute myeloid leukemia

Ballenga, Nariman, PhD
Signaling and function of G protein-coupled receptors in parathyroid tumors

Bar, Eli, PhD
Identification and targeting of cancer-cell intrinsic signaling nodes activated by signals from the tumor environment

Barry, Kathryn, PhD, MPH
Population studies in cancer occupational and environmental risk factors; cancer health disparities

Bromberg, Jonathan, MD, PhD
Population  studies in cancer occupational and environmental risk factors; cancer health disparities

Cao, Xuefang, MD, PhD
T cell biology, tumor immunity and transplantation immunity

Carrier, France, PhD
Genotoxic stress response, cancer progression, and radiobiology

Civin, Curt, MD
Cell and molecular biology of normal hematopoiesis and leukemia

Cullen, Kevin J., MD
Molecular markers of treatment response and outcome in head and neck cancer

Devine, Scott, PhD
Transposable genetic elements in human genome variation and cancer 

Dorgan, Joanne, PhD
Hormonal determinants of breast cancer; cancer risk via environmental and behavioral exposures, and genetics

Dunning Hotopp, Julie C., PhD 
Bacterial-animal lateral gene transfer; Integrations in the human cancer genome

Eckert, Richard, PhD 
Cancer stem cell survival factors as therapy targets for squamous cell carcinoma, melanoma, and mesothelioma

Fraser, Claire, PhD 
Human gut microbial communities in health, obesity, inflammatory bowel disease, and colon cancer   

Fulton, Amy, PhD
Cyclooxygenase pathway in tumor biology and metastasis; cancer disparities

Gravitt, Patti E., PhD 
HPV molecular diagnostics and translational research

Hassel, Bret A., PhD
Nathan Schnaper Intern Program in Translational Cancer Research 

He, Xiaoming, PhD
Development of multiscale (micro-nano-macro) technologies for delivery of cancer therapeutic agents

Hertzano, Ronna P., MD, PhD 
Diagnosis and treatment of diseases of the ear; hearing loss from chemotherapy; hearing restoration

Hussain, Arif, MD 
Targeting pathways of resistance to cytotoxic agents in prostate cancer

Jay, Steven, PhD 
HER3-targeted protein therapeutics; extracellular vesicles

Jewell, Christopher, PhD 
Immune engineering; synthetic materials, nano-technology

Jiang, Feng, MD, PhD 
Genomic and molecular genetic aberrations that lead to lung cancer

Jones, Laundette, PhD, MPH  
Cancer Health Disparities; Breast Cancer Survivorship; UMB Postbaccalaureate Research Education Program (PREP)

Jones, Lisa, PhD 
Developing new methods to study protein structure in-cell and in vivo; fast photo- oxidation of proteins (FPOP) coupled with mass spectrometry

Keegan, Achsah D., PhD
IL-4 and IL-13 signaling pathways in apoptosis, response to chemotherapy and macrophage phenotypes

Kim, Anthony, PhD 
Development of translational nanomedicine for CNS diseases, with a focus on brain cancers

Kingsbury, Tami, PhD 
Gene regulatory networks in hematopoiesis and stem cells

Kontrogianni-Konstantopoulos, Aikaterini, PhD 
Obscurins in skeletal & cardiac myopathies and tumor suppressor role in breast cancer 

Lin, Jiayuh, PhD
IL-6 signaling in pancreatic cancer

Losert, Wolfgang, PhD 
Systems biology, integrated mechanical and biochemical signals in cancer cell motility, and granular flows

Mackerell, Alexander D. Jr, PhD 
Drug design: force field development and computational studies of nucleic acids, proteins and carbohydrates

Martin, Stuart S., PhD 
Cytoskeletal and apoptotic determinants of circulating breast tumor cell survival and metastasis

Montaner, Sylvia, PhD 
Metastasis of oral cancers, molecular markers and therapeutic approaches for oral malignancies

Njar, Vincent, PhD 
Rational discovery and development of anti-cancer agents for breast, prostate and pancreatic cancers

Nowak, Rebecca G., PhD, MPH 
Molecular pathogenesis of virally associated cancers; HIV immunosuppression

O'Connor, Timothy, PhD 
Effects of evolution and population structure on genomic architecture of cancer and other diseases

Oakes, Robert (Smitty), PhD 
Immune engineering; synthetic materials, nano-technology

Olson, John, MD, PhD 
Mechanisms of tumor formation in primary hyperparathyroidism

Poulopoulos, Alexandros, PhD 
In vivo CRISPR genome editing; manipulation of neural circuits in the rodent brain

Qi, Jianfei, PhD 
Mechanisms regulating ubiquitin ligases and histone demethylases in prostate cancer

Qiu, Yun, PhD 
Molecular mechanisms of signal transduction by tyrosine kinases in prostate cancer progression

Rassool, Feyruz V., PhD 
DNA damage and repair in cancer and leukemia

Rathinam, Chozha, PhD 
Novel molecular pathways that control human stem cell biology

Schriml, Lynn, PhD 
Developing bioinformatic tools, metadata standards and ontologies; identify determinants of cancer etiology and survivorship

Singh, Nevil, PhD 
Immune activation, T cell tolerance; tumor immuno-therapy

Summers, Michael F., PhD 
Structure and function of retroviral proteins, mechanism of structural protein assembly and packaging

Vitolo, Michele I., PhD 
Molecular mechanisms by which PTEN loss promotes metastatic efficiency of circulating tumor cells

Vogel, Stefanie N., PhD 
Mechanisms by which macrophage differentiation facilitates or restricts tumor growth and viral infection

Wang, Jian-Ying, MD, PhD
Intestinal mucosal functions in growth and repair; colon cancer

Webb, Tonya, PhD 
Modulation of CD1d-mediated NKT cell activation for cancer immunotherapy

Weber, David J., PhD 
Structure and function of calcium-binding proteins, cancer biology and drug design

White, Ian, PhD 
Tools for diagnostics, extracellular vesicles and miRNA in cancer, biomarkers for early cancer diagnostics from liquid biopsies

Winkles, Jeffrey A., PhD 
TWEAK/Fn14 axis in brain and breast cancer

Woodworth, Graeme, MD 
Molecular mechanisms of glioblastoma margin (GBM); drug delivery by focused ultrasound

Zalzman, Michal, PhD  
Mechanisms controlling telomere maintenance and cellular lifespan