Cancer Biology T-32 Training Grant
For additional information about the program or the application process, please contact:
Leanne Simington, MS
Grants and Contracts Coordinator
University of Maryland School of Medicine
Marlene and Stewart Greenebaum Cancer Center
MSTF, 3-57 W, 3-57J
410 706-8358
lsimington@som.umaryland.edu
Toni M. Antalis, Ph.D.
Co-Director
Professor of Physiology,
University of Maryland School of Medicine
410 706-8222
tantalis@som.umaryland.edu
Curt I. Civin, M.D.
Co-Director
Associate Dean for Research,
University of Maryland School of Medicine
410 706-1198/1181
ccivin@som.umaryland.edu
Guidelines and Application 2020
The Cancer Biology T32 Training Program at the University of Maryland is a prestigious program designed to train predoctoral students and postdoctoral fellows in fundamental mechanisms of cancer biology at the molecular, cellular and organism levels. The program takes advantage of the multidisciplinary and highly interactive research environment within the University of Maryland Greenebaum Cancer Center and at the University of Maryland Baltimore campus to provide outstanding training in critical areas of basic and translational cancer research. A guiding philosophy is that Cancer Biology T32 training program must provide integrative activities that illuminate the inter-relatedness of basic cancer research and clinical medicine. Support for the program has been provided from a training grant from the NIH National Cancer Institute.
To be considered for a position on this training grant, the trainee should identify a faculty mentor and develop a research plan in conjunction with the mentor to be submitted with the application.
The award of a trainee slot on this grant is for a 1 year period, and is renewable by competitive application for a 2nd and possibly a 3rd year. Each year involves a competitive renewal with no greater assurance of funding for ongoing applicants than for new applicants. T32 supported trainees and mentors are strongly encouraged to apply for individual competitive fellowships or for other cancer research grant support during their 1st or 2nd year in the program. All predoctoral and postdoctoral fellows supported by the Cancer Biology T32 training program will be encouraged to participate in didactic components, interactive seminars and workshops, and professional development to appropriate to their background, in order to provide a solid foundation for a long term and successful career in cancer research.
The levels of funding support from the T32 grant are mandated by NIH guidelines (http://www.cancer.gov/researchandfunding/cancertraining/funding/T32). As appropriate, salary may be supplemented from other single or combined sources, such as research grants, professional fees, etc. Health insurance and support for travel is provided. For M.D. trainees, support from the T32 Training Program provides ‘protected time’ for immersion in the laboratory and it is required that patient care responsibilities will be limited to <10% effort (one half day per week), primarily to help complete long-term patient care experience necessary for their subspecialities and to maintain patient-care skills.
Qualifications for Trainee Slots:
• All appointments to this training grant are restricted to U.S. citizens and permanent residents.
• Applicants must be committed to cancer research.
• Predoctoral applicants must be enrolled in GPILS (PhD or MD/PhD program) at the University of Maryland Baltimore. Students must have completed the required courses: GPLS 790 - Advanced Cancer Biology and GPLS 665 - Cancer Biology: From Basic Research to the Clinic.
• Postdoctoral applicants must have completed doctoral level training (e.g. PhD, MD, MD/PhD, PharmD, DDS or equivalent). Evidence of scholarly productivity in the form of publications or planned publications is highly desirable. Post-doctoral trainees from Residency and Fellowship training programs (e.g. Radiation Oncology, Hematology/Oncology, and Oncology residents from OB-GYN, Otorhinolaryngology, Pathology, Pediatrics, Medicine or Surgery residency programs) are encouraged to apply.
Guidelines and Application 2020
Research by Faculty Members
Below is a list of faculty members along with the focus of their research. Click the name of a faculty member to see their Faculty Profile. Faculty profiles include detailed information and contact information.
Adebamowo, Clement A., MD Sc.D
The molecular biology of HPV associated cancer (cervical and head and neck cancer) and breast cancer
Antalis, Toni, PhD
Regulation of signaling pathways affecting cancer growth and metastasis, vascular biology, angiogenesis, and inflammation by serine proteases and their inhibitors
Baer, Maria, MD
Signaling pathways affecting drug resistance mechanisms in acute myeloid leukemia
Ballenga, Nariman, PhD
Signaling and function of G protein-coupled receptors in parathyroid tumors
Bar, Eli, PhD
Identification and targeting of cancer-cell intrinsic signaling nodes activated by signals from the tumor environment
Barry, Kathryn, PhD, MPH
Population studies in cancer occupational and environmental risk factors; cancer health disparities
Bromberg, Jonathan, MD, PhD
Population studies in cancer occupational and environmental risk factors; cancer health disparities
Cao, Xuefang, MD, PhD
T cell biology, tumor immunity and transplantation immunity
Carrier, France, PhD
Genotoxic stress response, cancer progression, and radiobiology
Civin, Curt, MD
Cell and molecular biology of normal hematopoiesis and leukemia
Cullen, Kevin J., MD
Molecular markers of treatment response and outcome in head and neck cancer
Devine, Scott, PhD
Transposable genetic elements in human genome variation and cancer
Dorgan, Joanne, PhD
Hormonal determinants of breast cancer; cancer risk via environmental and behavioral exposures, and genetics
Dunning Hotopp, Julie C., PhD
Bacterial-animal lateral gene transfer; Integrations in the human cancer genome
Eckert, Richard, PhD
Cancer stem cell survival factors as therapy targets for squamous cell carcinoma, melanoma, and mesothelioma
Fraser, Claire, PhD
Human gut microbial communities in health, obesity, inflammatory bowel disease, and colon cancer
Fulton, Amy, PhD
Cyclooxygenase pathway in tumor biology and metastasis; cancer disparities
Gravitt, Patti E., PhD
HPV molecular diagnostics and translational research
Hassel, Bret A., PhD
Nathan Schnaper Intern Program in Translational Cancer Research
He, Xiaoming, PhD
Development of multiscale (micro-nano-macro) technologies for delivery of cancer therapeutic agents
Hertzano, Ronna P., MD, PhD
Diagnosis and treatment of diseases of the ear; hearing loss from chemotherapy; hearing restoration
Hussain, Arif, MD
Targeting pathways of resistance to cytotoxic agents in prostate cancer
Jay, Steven, PhD
HER3-targeted protein therapeutics; extracellular vesicles
Jewell, Christopher, PhD
Immune engineering; synthetic materials, nano-technology
Jiang, Feng, MD, PhD
Genomic and molecular genetic aberrations that lead to lung cancer
Jones, Laundette, PhD, MPH
Cancer Health Disparities; Breast Cancer Survivorship; UMB Postbaccalaureate Research Education Program (PREP)
Jones, Lisa, PhD
Developing new methods to study protein structure in-cell and in vivo; fast photo- oxidation of proteins (FPOP) coupled with mass spectrometry
Keegan, Achsah D., PhD
IL-4 and IL-13 signaling pathways in apoptosis, response to chemotherapy and macrophage phenotypes
Kim, Anthony, PhD
Development of translational nanomedicine for CNS diseases, with a focus on brain cancers
Kingsbury, Tami, PhD
Gene regulatory networks in hematopoiesis and stem cells
Kontrogianni-Konstantopoulos, Aikaterini, PhD
Obscurins in skeletal & cardiac myopathies and tumor suppressor role in breast cancer
Lin, Jiayuh, PhD
IL-6 signaling in pancreatic cancer
Losert, Wolfgang, PhD
Systems biology, integrated mechanical and biochemical signals in cancer cell motility, and granular flows
Mackerell, Alexander D. Jr, PhD
Drug design: force field development and computational studies of nucleic acids, proteins and carbohydrates
Martin, Stuart S., PhD
Cytoskeletal and apoptotic determinants of circulating breast tumor cell survival and metastasis
Montaner, Sylvia, PhD
Metastasis of oral cancers, molecular markers and therapeutic approaches for oral malignancies
Njar, Vincent, PhD
Rational discovery and development of anti-cancer agents for breast, prostate and pancreatic cancers
Nowak, Rebecca G., PhD, MPH
Molecular pathogenesis of virally associated cancers; HIV immunosuppression
O'Connor, Timothy, PhD
Effects of evolution and population structure on genomic architecture of cancer and other diseases
Oakes, Robert (Smitty), PhD
Immune engineering; synthetic materials, nano-technology
Olson, John, MD, PhD
Mechanisms of tumor formation in primary hyperparathyroidism
Poulopoulos, Alexandros, PhD
In vivo CRISPR genome editing; manipulation of neural circuits in the rodent brain
Qi, Jianfei, PhD
Mechanisms regulating ubiquitin ligases and histone demethylases in prostate cancer
Qiu, Yun, PhD
Molecular mechanisms of signal transduction by tyrosine kinases in prostate cancer progression
Rassool, Feyruz V., PhD
DNA damage and repair in cancer and leukemia
Rathinam, Chozha, PhD
Novel molecular pathways that control human stem cell biology
Schriml, Lynn, PhD
Developing bioinformatic tools, metadata standards and ontologies; identify determinants of cancer etiology and survivorship
Singh, Nevil, PhD
Immune activation, T cell tolerance; tumor immuno-therapy
Summers, Michael F., PhD
Structure and function of retroviral proteins, mechanism of structural protein assembly and packaging
Vitolo, Michele I., PhD
Molecular mechanisms by which PTEN loss promotes metastatic efficiency of circulating tumor cells
Vogel, Stefanie N., PhD
Mechanisms by which macrophage differentiation facilitates or restricts tumor growth and viral infection
Wang, Jian-Ying, MD, PhD
Intestinal mucosal functions in growth and repair; colon cancer
Webb, Tonya, PhD
Modulation of CD1d-mediated NKT cell activation for cancer immunotherapy
Weber, David J., PhD
Structure and function of calcium-binding proteins, cancer biology and drug design
White, Ian, PhD
Tools for diagnostics, extracellular vesicles and miRNA in cancer, biomarkers for early cancer diagnostics from liquid biopsies
Winkles, Jeffrey A., PhD
TWEAK/Fn14 axis in brain and breast cancer
Woodworth, Graeme, MD
Molecular mechanisms of glioblastoma margin (GBM); drug delivery by focused ultrasound
Zalzman, Michal, PhD
Mechanisms controlling telomere maintenance and cellular lifespan